There is an unmet need for blood biomarkers in diagnosis and prognosis of chronic
obstructive pulmonary disease (COPD). The search for these biomarkers has been …

Rationale: A genome-wide association study (GWAS) for circulating chronic obstructive
pulmonary disease (COPD) biomarkers could identify genetic determinants of biomarker …

Chronic obstructive pulmonary disease (COPD) is a common and progressive disease that
is influenced by both genetic and environmental factors. For many years, knowledge of the …

Rationale: The ability of peripheral blood biomarkers to assess chronic obstructive
pulmonary disease (COPD) risk and progression is unknown. Genetics and gene …

High-throughput, genome-wide analytical technologies are now commonly used in all fields
of medical research. The most commonly applied of these technologies, gene expression …

The onset of chronic obstructive pulmonary disease (COPD) is heterogeneous, and current
approaches to define distinct disease phenotypes are lacking. In addition to clinical …

Chronic obstructive pulmonary disease (COPD) is a heterogeneous group of chronic lung
conditions. Genome-wide association studies have identified single-nucleotide …

Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disorder with
complex pathological features and largely unknown etiology. The identification of …

To better understand the molecular basis of chronic obstructive pulmonary disease (COPD),
we used serial analysis of gene expression (SAGE) and microarray analysis to compare the …

Since the discovery of alpha‐1 antitrypsin in the early 1960s, several new genes have been
suggested to play a role in chronic obstructive pulmonary disease (COPD) pathogenesis …