LncRNA MALAT1 promotes lung cancer proliferation and gefitinib resistance by acting as a miR-200a sponge

C Feng, Y Zhao, Y Li, T Zhang, Y Ma, Y Liu - … de Bronconeumología (English …, 2019 - Elsevier
Introducción El cáncer de pulmón es un importante problema de salud pública. Constituye
la segunda causa de muerte por cáncer en el mundo y se asocia a tasas de supervivencia …

[HTML][HTML] LncRNA MALAT1 exerts oncogenic functions in lung adenocarcinoma by targeting miR-204

J Li, J Wang, Y Chen, S Li, M Jin, H Wang… - American journal of …, 2016 - ncbi.nlm.nih.gov
Accumulating evidence indicates that the lncRNAs play a critical role in cancer progression
and metastasis. In this study, we found that MALAT1 upregulation was associated with larger …

LncRNA MALAT1 promotes migration and invasion of non-small-cell lung cancer by targeting miR-206 and activating Akt/mTOR signaling

Y Tang, GM Xiao, YJ Chen, Y Deng - Anti-Cancer Drugs, 2018 - journals.lww.com
Long noncoding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript 1
(MALAT1) functions as a crucial regulator of metastasis in lung cancer. The aim of this study …

[HTML][HTML] Functions and mechanisms of lncRNA MALAT1 in cancer chemotherapy resistance

J Hou, G Zhang, X Wang, Y Wang, K Wang - Biomarker research, 2023 - Springer
Chemotherapy is one of the most important treatments for cancer therapy. However,
chemotherapy resistance is a big challenge in cancer treatment. Due to chemotherapy …

LncRNA MALAT1 accelerates non‐small cell lung cancer progression via regulating miR‐185‐5p/MDM4 axis

D Wang, S Zhang, M Zhao, F Chen - Cancer medicine, 2020 - Wiley Online Library
Non‐small cell lung cancer (NSCLC) is the commonest malignancy with high death rate
around the world. LncRNA metastasis‐associated lung adenocarcinoma transcript 1 …

[HTML][HTML] LncRNA MALAT1 depressed chemo-sensitivity of NSCLC cells through directly functioning on miR-197-3p/p120 catenin axis

T Yang, H Li, T Chen, H Ren, P Shi, M Chen - Molecules and cells, 2019 - Elsevier
This study was aimed to explore if lncRNA MALAT1 would modify chemo-resistance of non-
small cell lung cancer (NSCLC) cells by regulating miR-197-3p and p120 catenin (p120 …

[HTML][HTML] LncRNA MALAT1 promotes breast cancer progression and doxorubicin resistance via regulating miR-570–3p

X Yue, W Wu, M Dong, M Guo - Biomedical journal, 2021 - Elsevier
Background Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a long
non-coding RNA (lncRNA) that regulates disease progression in various types of cancers …

Multiple function of lncRNA MALAT1 in cancer occurrence and progression

F Malakoti, N Targhazeh, H Karimzadeh… - Chemical biology & …, 2023 - Wiley Online Library
Long non‐coding RNAs (lncRNAs) have received particular attention in the last decade due
to its engaging in carcinogenesis and tumorigenesis. Metastasis‐associated lung …

[HTML][HTML] LncRNA-MALAT1 contributes to the cisplatin-resistance of lung cancer by upregulating MRP1 and MDR1 via STAT3 activation

Z Fang, W Chen, Z Yuan, X Liu, H Jiang - Biomedicine & Pharmacotherapy, 2018 - Elsevier
Multiple drug resistance is the main reason for chemotherapeutic failure in lung cancer
patients with complex molecular mechanisms. LncRNA-MALAT1 plays functional roles in the …

[HTML][HTML] LncRNA MALAT1 negatively regulates MDSCs in patients with lung cancer

Q Zhou, X Tang, X Tian, J Tian, Y Zhang, J Ma… - Journal of …, 2018 - ncbi.nlm.nih.gov
Myeloid-derived suppressor cells (MDSCs) have strong immunosuppressive functions and
contribute to the formation of the tumor microenvironment. Long non-coding (Lnc) RNAs are …