The exposome and health: Where chemistry meets biology
Despite extensive evidence showing that exposure to specific chemicals can lead to
disease, current research approaches and regulatory policies fail to address the chemical …
disease, current research approaches and regulatory policies fail to address the chemical …
The importance of the biological impact of exposure to the concept of the exposome
Background: The term “exposome” was originally coined in 2005 and defined as the totality
of exposures throughout the lifetime. The exposome provides an excellent scientific …
of exposures throughout the lifetime. The exposome provides an excellent scientific …
The nature of nurture: refining the definition of the exposome
Historical debates concerning human biology and behavior have frequently focused on
contributions of nature, ie, the inherited characteristics with which we are born, and nurture …
contributions of nature, ie, the inherited characteristics with which we are born, and nurture …
The exposome: molecules to populations
MM Niedzwiecki, DI Walker… - Annual review of …, 2019 - annualreviews.org
Derived from the term exposure, the exposome is an omic-scale characterization of the
nongenetic drivers of health and disease. With the genome, it defines the phenome of an …
nongenetic drivers of health and disease. With the genome, it defines the phenome of an …
The exposome and toxicology: a win–win collaboration
R Barouki, K Audouze, C Becker, L Blaha… - Toxicological …, 2022 - academic.oup.com
The development of the exposome concept has been one of the hallmarks of environmental
and health research for the last decade. The exposome encompasses the life course …
and health research for the last decade. The exposome encompasses the life course …
Implications of the exposome for exposure science
SM Rappaport - Journal of exposure science & environmental …, 2011 - nature.com
During the 1920s, the forerunners of exposure science collaborated with health
professionals to investigate the causes of occupational diseases. With the birth of US …
professionals to investigate the causes of occupational diseases. With the birth of US …
Exposure science and the exposome: an opportunity for coherence in the environmental health sciences
PJ Lioy, SM Rappaport - Environmental health perspectives, 2011 - ehp.niehs.nih.gov
The field of exposure science began with qualitative observations and quantitative
measurements of air contaminants to aid our under standing of exposure–disease …
measurements of air contaminants to aid our under standing of exposure–disease …
The Eco‐Exposome concept: Supporting an integrated assessment of mixtures of environmental chemicals
Organisms are exposed to ever‐changing complex mixtures of chemicals over the course of
their lifetime. The need to more comprehensively describe this exposure and relate it to …
their lifetime. The need to more comprehensively describe this exposure and relate it to …
[HTML][HTML] What is new in the exposome?
P Vineis, O Robinson, M Chadeau-Hyam… - Environment …, 2020 - Elsevier
The exposome concept refers to the totality of exposures from a variety of external and
internal sources including chemical agents, biological agents, or radiation, from conception …
internal sources including chemical agents, biological agents, or radiation, from conception …
[HTML][HTML] Merging the exposome into an integrated framework for “omics” sciences
The exposome concept encourages holistic consideration of the non-genetic factors
(environmental exposures including lifestyle) that influence an individual's health over their …
(environmental exposures including lifestyle) that influence an individual's health over their …