Alterations in gray matter (GM) density/volume and cortical thickness (CT) have been
demonstrated in small and heterogeneous samples of subjects with differing chronic pain …

BACKGROUND & AIMS: Several studies have examined structural brain changes
associated with chronic pain syndromes, including irritable bowel syndrome (IBS), but study …

Background & Aims Regional reductions in gray matter (GM) have been reported in several
chronic somatic and visceral pain conditions, including irritable bowel syndrome (IBS) and …

BACKGROUND & AIMS: Brain imaging studies have identified abnormal rectal-evoked
responses and cortical thinning in patients with irritable bowel syndrome (IBS). However, it is …

Increased perception of visceral stimuli is a key feature of Irritable Bowel Syndrome (IBS).
While altered resting-state functional connectivity (rsFC) has been also reported in IBS, the …

Background Increased attention to gastrointestinal (GI) symptoms and disease‐specific
contexts may play an important role in the enhanced perception of visceral stimuli frequently …

Abstract Changes in brain-gut interactions have been implicated in the pathophysiology of
chronic visceral pain in irritable bowel syndrome (IBS). Different mechanisms of sensitization …

Objective Imaging studies in adults with irritable bowel syndrome (IBS) have shown both
morphological and resting state (RS) functional connectivity (FC) alterations related to …

Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder resulting
from a dysregulation of the brain-gut axis. However, its exact neural substrate still remains …

Greater responsiveness of emotional arousal circuits in relation to delivered visceral pain
has been implicated as underlying central pain amplification in irritable bowel syndrome …