[HTML][HTML] Roles of AMP-activated protein kinase (AMPK) in mammalian reproduction

W Yang, L Wang, F Wang, S Yuan - Frontiers in Cell and …, 2020 - frontiersin.org
Reproduction is an energy demanding function and only take place in case of sufficient
available energy status in mammals. Metabolic diseases such as anorexia nervosa are …

Role of AMPK in mammals reproduction: Specific controls and whole-body energy sensing

TMD Nguyen - Comptes Rendus Biologies, 2019 - Elsevier
AMP-activated protein kinase (AMPK) is a key enzyme involved in linking the energy
sensing to metabolic pathways. As such, it plays a central role at the whole-body level to …

AMPK: a master energy regulator for gonadal function

MJ Bertoldo, M Faure, J Dupont… - Frontiers in neuroscience, 2015 - frontiersin.org
From C. elegans to mammals (including humans), nutrition and energy metabolism
significantly influence reproduction. At the cellular level, some detectors of energy status …

Inactivation of AMPKα1 induces asthenozoospermia and alters spermatozoa morphology

P Tartarin, E Guibert, A Toure, C Ouiste… - …, 2012 - academic.oup.com
AMP-activated protein kinase (AMPK), a key regulator of cellular energy homeostasis, is
present in metabolic tissues (muscle and liver) and has been identified as a modulator of the …

AMPK function in mammalian spermatozoa

D Martin-Hidalgo, A Hurtado de Llera… - International journal of …, 2018 - mdpi.com
AMP-activated protein kinase AMPK regulates cellular energy by controlling metabolism
through the inhibition of anabolic pathways and the simultaneous stimulation of catabolic …

Pharmacological and morphological evidence of AMPK-mediated energy sensing in the lower brain stem ependymocytes to control reproduction in female rodents

S Minabe, C Deura, K Ikegami, T Goto, M Sanbo… - …, 2015 - academic.oup.com
Ependymocytes are one of the energy-sensing cells that regulate animal reproduction
through their responsiveness to changes in extracellular glucose levels and the expression …

AMPK, regulator of sperm energy and functions

TM Nguyen, P Froment, Y Combarnous… - … Sciences: M/S, 2016 - europepmc.org
The 5'-AMP-activated protein kinase, AMPK, is a key protein kinase in the metabolism of the
cell that regulates many metabolic pathways. The involvement of cell metabolism in sperm …

At the crossroads of fertility and metabolism: The importance of AMPK-dependent signaling in female infertility associated with hyperandrogenism

P Froment, I Plotton, C Giulivi, S Fabre… - Human …, 2022 - academic.oup.com
STUDY QUESTION What biological processes are linked to the signaling of the energy
sensor 5′-AMP-activated protein kinase (AMPK) in mouse and human granulosa cells …

AMP-activated kinase AMPK is expressed in boar spermatozoa and regulates motility

A Hurtado de Llera, D Martin-Hidalgo, MC Gil… - PloS one, 2012 - journals.plos.org
The main functions of spermatozoa required for fertilization are dependent on the energy
status and metabolism. AMP-activated kinase, AMPK, acts a sensor and regulator of cell …

[HTML][HTML] Impact of 5'-amp-activated protein kinase on male gonad and spermatozoa functions

TMD Nguyen - Frontiers in Cell and Developmental Biology, 2017 - frontiersin.org
As we already know, the male reproductive system requires less energetic investment than
the female one. Nevertheless, energy balance is an important feature for spermatozoa …