A quantum-dot-based nanoparticle is presented, allowing visualization of cell death and
activated platelets with fluorescence imaging and MRI. The particle exhibits intense …

Apoptosis, or programmed cell death, plays an important role in the etiology of a variety of
diseases, including cancer. Visualization of apoptosis would allow both early detection of …

Quantum dots (Qdots) are nanoparticles exhibiting fluorescent properties that can be used
for cell staining. We present here the development of quantum dots conjugated to Annexin V …

MRI detectable and targeted quantum dots were developed. To that aim, quantum dots were
coated with paramagnetic and pegylated lipids, which resulted in a relaxivity, r 1, of nearly …

Apoptosis and macrophage burden are believed to correlate with atherosclerotic plaque
vulnerability and are therefore considered important diagnostic and therapeutic targets for …

Annexin V, which recognizes the phosphatidylserine of apoptotic cells, was conjugated to
crosslinked iron oxide (CLIO) nanoparticles, a functionalized superparamagnetic …

Imaging of apoptosis can allow noninvasive assessment of disease states and response to
therapeutic intervention for a variety of diseases. The purpose of this study was to develop …

Quantum dots (QDs), semiconductor nanocrystals, are fluorescent nanoparticles of growing
interest as an imaging tool of a diseased tissue. However, a major concern is their …

A biocompatible surface-functionalized nanoparticle was designed to sense
phosphatidylserine exposed on apoptotic cells. We conjugated synthetic artificial …

New nanomaterials intended for systemic administration have raised concerns regarding
their biocompatibility and hemocompatibility. Quantum dots (QD) nanoparticles have been …