Acetaminophen is a commonly used analgesic and antipyretic drug, high doses of which
cause hepatic and renal injury. In development and progression of kidney disease research …

Acetaminophen (APAP), also known as paracetamol, is the commonest cause of toxic
ingestion in the world. Because overdose of APAP has life-threatening effects on kidney …

Acute acetaminophen (APAP) nephrotoxicity was studied in male Wistar rats 1 h after
different APAP single doses (200, 500 and 1000 mg/kg body wt, ip). Significant impairments …

The aim of the present study was to evaluate the sub-acute oral toxicity of acetaminophen in
Sprague Dawley (SD) rats at 250 to 1000 mg/kg body weight (b. wt.). The following …

The incidence of acetaminophen-induced nephropathy is reported to be increasing, with no
available prophylactic or curative regimen. The present study is an experimental animal …

AIMS: Acetaminophen is a safe antipyretic and analgesic drug within the clinically
recommended dosage range, but overdose can cause fatal liver and or kidney damage …

Introduction: Acetaminophen (APAP) is an analgesic and antipyretic agent. In overdoses, it
is associated with nephrotoxicity. We examined the potential protective effects of N …

Acetaminophen (APAP) can cause life-threatening renal damages and there is no specific
treatment for APAP-induced renal damage. The aim of this study was to investigate the …

The present investigation was planned to evaluate the nephroprotective activity of jaggery
against acetaminophen (APAP)-induced renal damage in rats. The protective activity of …

This study was aimed to evaluate the preventive efficacy of syringic acid (SA) on
acetaminophen (APAP)-induced nephrotoxicity. Nephrotoxicity was induced in male Wistar …