Using Raman spectroscopy to characterize biological materials

HJ Butler, L Ashton, B Bird, G Cinque, K Curtis… - Nature protocols, 2016 - nature.com
Raman spectroscopy can be used to measure the chemical composition of a sample, which
can in turn be used to extract biological information. Many materials have characteristic …

Advances in biomedical Raman microscopy

KA Antonio, ZD Schultz - Analytical chemistry, 2014 - ACS Publications
The vibrational modes of molecules provide an intrinsic contrast mechanism for identifying
components in cells, tissues, and organisms. When excited by a laser, Raman scattered …

Chemometric analysis in Raman spectroscopy from experimental design to machine learning–based modeling

S Guo, J Popp, T Bocklitz - Nature protocols, 2021 - nature.com
Raman spectroscopy is increasingly being used in biology, forensics, diagnostics,
pharmaceutics and food science applications. This growth is triggered not only by …

Raman imaging from microscopy to macroscopy: quality and safety control of biological materials

S Lohumi, MS Kim, J Qin, BK Cho - TrAC Trends in Analytical Chemistry, 2017 - Elsevier
Raman imaging can analyze biological materials by generating detailed chemical images.
Over the past decade, significant advancements in Raman imaging and data analysis …

Advances in Raman spectroscopy and imaging for biomedical research

S Siddhanta, AN Kuzmin, A Pliss, AS Baev… - Advances in Optics …, 2023 - opg.optica.org
Starting with a historical account of evolution in Raman spectroscopy, in this review we
provide details of the advancements that have pushed detection limits to single molecules …

Chemical analysis in vivo and in vitro by Raman spectroscopy—from single cells to humans

S Wachsmann-Hogiu, T Weeks, T Huser - Current opinion in biotechnology, 2009 - Elsevier
The gold standard for clinical diagnostics of tissues is immunofluorescence staining. Toxicity
of many fluorescent dyes precludes their application in vivo. Raman spectroscopy, a …

Raman spectroscopy for chemical biology research

K Dodo, K Fujita, M Sodeoka - Journal of the American Chemical …, 2022 - ACS Publications
In chemical biology research, various fluorescent probes have been developed and used to
visualize target proteins or molecules in living cells and tissues, yet there are limitations to …

Label-free molecular imaging and analysis by Raman spectroscopy

Y Kumamoto, Y Harada, T Takamatsu… - Acta histochemica et …, 2018 - jstage.jst.go.jp
Raman scattering of a cell conveys the intrinsic information inherent to chemical structures of
biomolecules. The spectroscopy of Raman scattering, or Raman spectroscopy, allows label …

Chemically sensitive bioimaging with coherent Raman scattering

CH Camp Jr, MT Cicerone - Nature photonics, 2015 - nature.com
Raman scattering provides an intrinsic fingerprint of chemical composition. Spontaneous
Raman spectroscopy has been used for many decades to interrogate biological materials …

Raman spectroscopy in cell biology and microbiology

G Pezzotti - Journal of Raman Spectroscopy, 2021 - Wiley Online Library
The Raman spectrum of living cells and microorganisms contains highly specific fingerprint‐
like signatures, useful in unequivocally identifying different species and interpreting …