Background. The autonomic storm accompanying brain death leads to neurogenic
pulmonary edema and triggers development of systemic and pulmonary inflammatory …

Brain-dead donors are the major source of lungs for transplantation. Brain death is
characterized by two hemodynamic phases. Initially, massive sympathetic discharge results …

Sympathetic discharge and hypertensive crisis often accompany brain death, causing
neurogenic pulmonary edema. Progressive systemic inflammatory response develops …

Objective: Two series of experiments were designed to evaluate whether early arginine
vasopressin improves acute outcome following resuscitation from traumatic brain injury and …

In a prospective study, we documented the hemodynamic effects of conventional donor
maintenance in 24 brain-dead organ donors. Patients were then randomized to receive …

Background. For better management of brain-dead donors, we developed a small animal
model of brain death. We investigated how three catecholamines commonly used for the …

The demand for donor organs continues to exceed the number of organs available for
transplantation. Many reasons may account for this discrepancy, such as the lack of consent …

Background Hormone replacement therapy (HRT) is becoming more common when
managing brain-dead donors. Arginine vasopressin (AVP) is associated with benefits but is …

We sought to determine the effects of a combination of vasopressin and epinephrine on
neurologic recovery in comparison with epinephrine alone and saline placebo alone in an …

We compared the effects of hormone resuscitation (HR) with a norepinephrine-based
protocol on cardiac function, hemodynamics and need for vasopressor support after brain …