Satellite glial cells (SGCs) are among the most abundant non-neuronal cells in dorsal root
ganglia (DRGs) and closely envelop sensory neurons that detect painful stimuli. However …

Peripheral sensory neurons located in dorsal root ganglia relay sensory information from the
peripheral tissue to the brain. Satellite glial cells (SGCs) are unique glial cells that form an …

Preclinical studies have identified glial cells as pivotal players in the genesis and
maintenance of neuropathic pain after nerve injury associated with diabetes, chemotherapy …

Satellite glial cells (SGCs) of dorsal root ganglia (DRGs) are activated in a variety of chronic
pain conditions; however, their mediation roles in pain remain elusive. Here, we take …

Chronic pain is one of the most prevalent chronic diseases in the world. The plastic changes
of sensory neurons in dorsal root ganglia (DRG) have been extensively studied as the …

Dorsal root ganglion (DRG) neurons detect sensory inputs and are crucial for pain
processing. They are often studied in vitro as dissociated cell cultures with the assumption …

Background: Satellite glial cells (SGCs) tightly surround and support primary sensory
neurons in the peripheral nervous system and are increasingly recognized for their …

Chronic pain is known to be caused by sensitization within the pain circuits. An imbalance
occurs between excitatory and inhibitory transmission that enables this sensitization to form …

Paralleling the activation of dorsal horn microglia after peripheral nerve injury is a significant
expansion and proliferation of macrophages around injured sensory neurons in dorsal root …

Peripheral nerve injury-induced neuropathic pain is a chronic and debilitating condition
characterized by mechanical hypersensitivity. We previously identified microglial activation …