Sequential endoluminal gemcitabine and docetaxel for the treatment of clinically non-invasive high-grade upper tract urothelial carcinoma

IM McElree, A Belzer, SL Mott, VT Packiam… - … Oncology: Seminars and …, 2024 - Elsevier
Purpose There is an unmet need for effective renal sparing treatments for upper tract
urothelial carcinoma (UTUC). Gemcitabine/Docetaxel (Gem/Doce) has shown favorable …

Multicenter phase II clinical trial of gemcitabine and cisplatin as neoadjuvant chemotherapy for patients with high-grade upper tract urothelial carcinoma

JA Coleman, W Yip, NC Wong, DD Sjoberg… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE Neoadjuvant chemotherapy (NAC) has proven survival benefits for patients with
invasive urothelial carcinoma of the bladder, yet its role for upper tract urothelial carcinoma …

Sequential endoluminal gemcitabine and docetaxel vs. Bacillus Calmette–Guérin for the treatment of upper tract carcinoma in situ

IM McElree, SL Mott, HY Hougen, VT Packiam… - … Oncology: Seminars and …, 2024 - Elsevier
Introduction Nephroureterectomy is commonly performed for high-grade (HG) upper tract
(UT) urothelial carcinoma (UC). However, some patients may benefit from a de-escalation of …

Sequential chemotherapy using gemcitabine+ carboplatin followed by gemcitabine+ carboplatin+ docetaxel for advanced upper-tract urothelial cancer

T Yoneyama, A Imai, S Hatakeyama… - International journal of …, 2015 - Springer
Background Retrospective evaluation of the effectiveness and adverse events (AEs) of a
sequential chemotherapy regimen using gemcitabine+ carboplatin (GCarbo) followed by …

Final results of a multicenter prospective phase II clinical trial of gemcitabine and cisplatin as neoadjuvant chemotherapy in patients with high-grade upper tract …

W Yip, J Coleman, NC Wong, DD Sjoberg, BH Bochner… - 2022 - ascopubs.org
440 Background: Neoadjuvant chemotherapy (NAC) has proven survival benefits for
invasive urothelial carcinoma of the bladder, yet its role in upper tract urothelial carcinoma …

Early outcomes with neoadjuvant high-dose intensity methotrexate, vinblastine, doxorubicin, and cisplatin (HD-MVAC) or gemcitabine and cisplatin (GC) in muscle …

N Mitra, JP Monk III, KS Pohar, A Shabsigh… - Journal of Clinical …, 2011 - ascopubs.org
280 Background: Compared to MVAC, HD-MVAC achieves significantly higher complete
response rates in patients (pts) with metastatic bladder cancer. Based on current literature …

Neoadjuvant chemotherapy with gemcitabine/cisplatin vs. methotrexate/vinblastine/doxorubicin/cisplatin for muscle-invasive urothelial carcinoma of the bladder: a …

AS Fairey, S Daneshmand, D Quinn, T Dorff… - … Oncology: Seminars and …, 2013 - Elsevier
Objectives We evaluated pathologic and survival outcomes of GC (gemcitabine/cisplatin)
and methotrexate/vinblastine/doxorubicin/cisplatin (M-VAC) neoadjuvant chemotherapy …

LBA-17 Multicenter prospective phase II clinical trial of gemcitabine and cisplatin as neoadjuvant chemotherapy in patients with high-grade upper tract urothelial …

JA Coleman*, NC Wong, DD Sjoberg, N Silva… - The Journal of …, 2019 - auajournals.org
INTRODUCTION AND OBJECTIVES: Neoadjuvant chemotherapy (NAC) has established
survival benefits prior to radical cystectomy for invasive urothelial carcinoma, yet its role in …

[HTML][HTML] Improving the outcome of patients with muscle invasive urothelial carcinoma of the bladder with neoadjuvant gemcitabine/cisplatin chemotherapy: A single …

F El-Gehani, S North, S Ghosh… - Canadian Urological …, 2014 - ncbi.nlm.nih.gov
Methods: This retrospective chart review examined all patients having a RC between
January 1, 2007 and June 30, 2011. We collected patient demographics, pre-treatment …

ONCOLOGIC OUTCOMES OF BLADDER-SPARING MANAGEMENT FOR HIGH-GRADE NON-INVASIVE UROTHELIAL CARCINOMA OF THE PROSTATIC …

AC Martin, IM McElree, SL Mott, JR Richards… - … Oncology: Seminars and …, 2024 - Elsevier
Introduction Among patients with high-grade (HG) non-muscle invasive urothelial carcinoma
(UC) of the bladder, prostatic urethral involvement occurs in 16-39%. Management of …