Silk fibroin hydrogels could Be therapeutic biomaterials for neurological diseases

C Yang, S Li, X Huang, X Chen, H Shan… - Oxidative Medicine …, 2022 - Wiley Online Library
Silk fibroin, a natural macromolecular protein without physiological activity, has been widely
used in different fields, such as the regeneration of bones, cartilage, nerves, and other …

Effect of silk fibroin on neuroregeneration after traumatic brain injury

MM Moisenovich, EY Plotnikov, AM Moysenovich… - Neurochemical …, 2019 - Springer
Traumatic brain injury is one of the leading causes of disability among the working-age
population worldwide. Despite attempts to develop neuroprotective therapeutic approaches …

[HTML][HTML] Silk fibroin: An ancient material for repairing the injured nervous system

M Yonesi, M Garcia-Nieto, GV Guinea, F Panetsos… - Pharmaceutics, 2021 - mdpi.com
Silk refers to a family of natural fibers spun by several species of invertebrates such as
spiders and silkworms. In particular, silkworm silk, the silk spun by Bombyx mori larvae, has …

Safety and tolerability of silk fibroin hydrogels implanted into the mouse brain

L Fernández-García, N Marí-Buyé, JA Barios… - Acta biomaterialia, 2016 - Elsevier
At present, effective therapies to repair the central nervous system do not exist. Biomaterials
might represent a new frontier for the development of neurorestorative therapies after brain …

Silk fibroin in wound healing process

MT Sultan, OJ Lee, SH Kim, HW Ju, CH Park - Novel Biomaterials for …, 2018 - Springer
Silk fibroin (SF), a natural bioproduct, has been extensively used in biological and
biomedical fields including wound healing due to its robust biocompatibility, less …

[HTML][HTML] Identification and applications of neuroactive silk proteins: A narrative review

A Banagozar Mohammadi, S Sadigh-Eteghad… - Journal of Applied …, 2019 - jab.zsf.jcu.cz
In traditional medicine, natural silk is regarded as a cognitive enhancer and a cure for
ameliorating the symptoms of heart disease, atherosclerosis, and metabolic disorders. In this …

Silk fibroin hydrogels for biomedical applications

H Zhang, D Xu, Y Zhang, M Li, R Chai - Smart Medicine, 2022 - Wiley Online Library
Silk fibroin hydrogels occupy an essential position in the biomedical field due to their
remarkable biological properties, excellent mechanical properties, flexible processing …

[HTML][HTML] Resistance to Degradation of Silk Fibroin Hydrogels Exposed to Neuroinflammatory Environments

M Yonesi, M Ramos, C Ramirez-Castillejo… - Polymers, 2023 - mdpi.com
Central nervous system (CNS) diseases represent an extreme burden with significant social
and economic costs. A common link in most brain pathologies is the appearance of …

[HTML][HTML] Silk fibroin biomaterials and their beneficial role in skin wound healing

Ł Mazurek, M Szudzik, M Rybka, M Konop - Biomolecules, 2022 - mdpi.com
The skin, acting as the outer protection of the human body, is most vulnerable to injury.
Wound healing can often be impaired, leading to chronic, hard-to-heal wounds. For this …

[HTML][HTML] Silk fibroin-based therapeutics for impaired wound healing

T Lehmann, AE Vaughn, S Seal, KW Liechty, C Zgheib - Pharmaceutics, 2022 - mdpi.com
Impaired wound healing can lead to local hypoxia or tissue necrosis and ultimately result in
amputation or even death. Various factors can influence the wound healing environment …