Drugs that have narrow absorption window in the gastrointestinal tract (GIT) will have poor
absorption. For these drugs, gastroretentive drug delivery systems offer the advantage in …

Oral sustained release gastroretentive dosage forms offer many advantages for drugs
having absorption from upper gastrointestinal tract and improve the bioavailability of …

Sustained release (SR)-gastroretentive dosage forms (GRDF) enable prolonged and
continuous input of the drug to the upper parts of the gastrointestinal (GI) tract and improve …

Ciprofloxacin hydrochloride has a short elimination half-life, a narrow absorption window
and is mainly absorbed in proximal areas of GIT. The purpose of this study was to develop a …

This study aimed to develop hydrophilic matrix based controlled release gastroretentive
drug delivery system of ofloxacin and conducting its in vitro and in vivo evaluations …

Context: One among many strategies to prolong gastric residence time and improve local
effect of the metronidazole in stomach to eradicate Helicobacter pylori in the treatment of …

The most common approach for achieving sustained drug release is by the use of
hydrophilic polymeric excipients directly compressed with active ingredients into tablets …

Sustained release gastroretentive dosage forms enable prolonged and continuous input of
the drug to the upper parts of gastrointestinal tract and improve the bioavailability of …

The fluroquinolone anti-biotic ciprofloxacin is primarily dissolved and absorbed from the
upper part of the GI tract. We, therefore, aimed to develop a prolonged release …

The purpose of this research was to develop a novel gastroretentive drug delivery system
based on effervescent technology for controlled delivery of active agent. Glipizide, a poorly …