[HTML][HTML] Development and validation of a scoring system to predict outcomes of vedolizumab treatment in patients with Crohn's disease
Background & Aims As more treatment options for inflammatory bowel diseases become
available, it is important to identify patients most likely to respond to different therapies. We …
available, it is important to identify patients most likely to respond to different therapies. We …
Predicting corticosteroid-free biologic remission with vedolizumab in Crohn's disease
Abstract Background and Aims Vedolizumab (VDZ) is effective for Crohn's disease (CD) but
costly and is slow to produce remission. Early knowledge of whether vedolizumab is likely to …
costly and is slow to produce remission. Early knowledge of whether vedolizumab is likely to …
Vedolizumab as induction and maintenance therapy for Crohn's disease
WJ Sandborn, BG Feagan, P Rutgeerts… - … England Journal of …, 2013 - Mass Medical Soc
Background The efficacy of vedolizumab, an α4β7 integrin antibody, in Crohn's disease is
unknown. Methods In an integrated study with separate induction and maintenance trials …
unknown. Methods In an integrated study with separate induction and maintenance trials …
Three‐year effectiveness and safety of vedolizumab therapy for inflammatory bowel disease: a prospective multi‐centre cohort study
A Amiot, M Serrero, L Peyrin‐Biroulet… - Alimentary …, 2019 - Wiley Online Library
Background Cohort studies have described the short‐term effectiveness and safety of
vedolizumab in treating patients with Crohn's disease (CD) and ulcerative colitis (UC), but …
vedolizumab in treating patients with Crohn's disease (CD) and ulcerative colitis (UC), but …
Comparative safety and effectiveness of vedolizumab to tumour necrosis factor antagonist therapy for Crohn's disease
M Bohm, R Xu, Y Zhang, S Varma… - Alimentary …, 2020 - Wiley Online Library
Background Direct comparisons are lacking between vedolizumab and tumour necrosis
factor (TNF)‐antagonist therapy in Crohn's disease (CD). Aim To compare safety and …
factor (TNF)‐antagonist therapy in Crohn's disease (CD). Aim To compare safety and …
Vedolizumab as induction and maintenance therapy for Crohn's disease in patients naïve to or who have failed tumor necrosis factor antagonist therapy
BE Sands, WJ Sandborn, G Van Assche… - Inflammatory bowel …, 2017 - academic.oup.com
Background Vedolizumab is a gut-selective α4β7 integrin antagonist for the treatment of
moderately to severely active Crohn's disease (CD). Aims of this study were to characterize …
moderately to severely active Crohn's disease (CD). Aims of this study were to characterize …
Vedolizumab induces endoscopic and histologic remission in patients with Crohn's disease
M Löwenberg, S Vermeire, N Mostafavi, F Hoentjen… - Gastroenterology, 2019 - Elsevier
Background & Aims We evaluated the ability of vedolizumab to induce endoscopic and
histologic remission in patients with Crohn's disease (CD). Methods We performed a …
histologic remission in patients with Crohn's disease (CD). Methods We performed a …
[HTML][HTML] Endoscopic, radiologic, and histologic healing with vedolizumab in patients with active Crohn's disease
S Danese, WJ Sandborn, JF Colombel, S Vermeire… - Gastroenterology, 2019 - Elsevier
Background & Aims Vedolizumab is a gut-selective monoclonal antibody for the treatment of
moderately to severely active Crohn's disease (CD). We performed a prospective study of …
moderately to severely active Crohn's disease (CD). We performed a prospective study of …
A clinical decision support tool may help to optimise vedolizumab therapy in Crohn's disease
PS Dulai, A Amiot, L Peyrin‐Biroulet… - Alimentary …, 2020 - Wiley Online Library
Background A clinical decision support tool (CDST) has been validated for predicting
treatment effectiveness of vedolizumab (VDZ) in Crohn's disease. Aim To assess the utility of …
treatment effectiveness of vedolizumab (VDZ) in Crohn's disease. Aim To assess the utility of …
Loss of response to vedolizumab and ability of dose intensification to restore response in patients with Crohn's disease or ulcerative colitis: a systematic review and …
L Peyrin-Biroulet, S Danese, M Argollo… - Clinical …, 2019 - Elsevier
Background & Aims Vedolizumab is effective and safe for the treatment of Crohn's disease
(CD) and ulcerative colitis (UC). Little is known about the incidence rate of loss of response …
(CD) and ulcerative colitis (UC). Little is known about the incidence rate of loss of response …
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