Preformulation studies are the physical, chemical, and biological studies needed to
characterize a drug substance for enabling the proper design of a drug product, whereas the …

Preformulation is a group of studies that focus on the physicochemical properties of a new
drug candidate that could affect the drug performance and the development of a dosage …

Historically, preformulation evolved in the late 1950s and early 1960s as a result of a shift in
emphasis in industrial pharmaceutical product development. Up until the mid1950s, the …

A typical product lifecycle stage is fraught with challenges right from the inception, ie, early
drug discovery/lead optimization to product development. Challenge includes optimization …

Preformulation testing is the first step in the rational development of dosage forms of a drug
substance, It can be defined as an investigation of physical and chemical properties of a …

The first edition of this book published in 2001 has been more successful than I ever
imagined, as indicated by the excellent reviews it has received, the continued demand, and …

Activities done prior to formulation development are called as preformulation studies. It
provides the scientific basis for formulation development. Preformulation studies can be …

In recent years, there has been a significant increase in pressure on pharmaceutical
companies to discover and develop new medicines ever faster to replace those coming off …

Prior to nomination into full development, a candidate drug should undergo a phase
traditionally called preformulation. Preformulation is the physicochemical characterization of …

• Knowledge of solubility and partition coefficient allows a Biopharmaceutics Classification
System (BCS) category to be assigned to the drug candidate, which gives an indication of …