A tendency in cell biology is to divide and conquer. For example, decades of painstaking
work have led to an understanding of endoplasmic reticulum (ER) and Golgi structure …

The organization, assembly and remodeling of the actin cytoskeleton provide force and
tracks for a variety of (endo) membrane-associated events such as membrane trafficking …

The plasma membrane (PM) and its associated cargo are internalized into small vesicles via
endocytosis funneling cargo into endosomes. The endosomal system must efficiently deliver …

In this review we describe the potential roles of the actin cytoskeleton in receptor-mediated
endocytosis in mammalian cells and summarize the efforts of recent years in establishing a …

Actin filaments play multiple roles in the secretory pathway and in endosome dynamics in
mammals, including maintenance of Golgi structure, release of membrane cargo from the …

The endoplasmic reticulum (ER) and Golgi have robust bidirectional traffic between them
and yet form distinct membrane compartments. Membrane tubules are pulled from large …

Association of the Golgi complex with cytoskeletal elements, in particular microtubules, is
required for maintenance of the Golgi's characteristic spatial location within cells and for …

Secretion and endocytosis are highly dynamic processes that are sensitive to external
stimuli. Thus, in multicellular organisms, different cell types utilize specialised pathways of …

Mechanobiology studies the mechanisms by which cells sense and respond to physical
forces, and the role of these forces in shaping cells and tissues themselves …

Membrane trafficking plays a crucial role in cell polarity by directing lipids and proteins to
specific subcellular locations in the cell and sustaining a polarized state. The Golgi …