Arabidopsis circadian clock protein, TOC1, is a DNA-binding transcription factor

JM Gendron, JL Pruneda-Paz… - Proceedings of the …, 2012 - National Acad Sciences
The first described feedback loop of the Arabidopsis circadian clock is based on reciprocal
regulation between TIMING OF CAB EXPRESSION 1 (TOC1) and CIRCADIAN CLOCK …

A Functional Genomics Approach Reveals CHE as a Component of the Arabidopsis Circadian Clock

JL Pruneda-Paz, G Breton, A Para, SA Kay - Science, 2009 - science.org
Transcriptional feedback loops constitute the molecular circuitry of the plant circadian clock.
In Arabidopsis, a core loop is established between CCA1 and TOC1. Although CCA1 …

A Complex Genetic Interaction Between Arabidopsis thaliana TOC1 and CCA1/LHY in Driving the Circadian Clock and in Output Regulation

Z Ding, MR Doyle, RM Amasino, SJ Davis - Genetics, 2007 - academic.oup.com
It has been proposed that CIRCADIAN CLOCK ASSOCIATED 1 (CCA1) and LATE
ELONGATED HYPOCOTYL (LHY) together with TIMING OF CAB EXPRESSION 1 (TOC1) …

A Functional Link between Rhythmic Changes in Chromatin Structure and the Arabidopsis Biological Clock

M Perales, P Más - The Plant Cell, 2007 - academic.oup.com
Circadian clocks rhythmically coordinate biological processes in resonance with the
environmental cycle. The clock function relies on negative feedback loops that generate 24 …

Loss of the circadian clock-associated protein 1 in Arabidopsis results in altered clock-regulated gene expression

RM Green, EM Tobin - … of the National Academy of Sciences, 1999 - National Acad Sciences
Little is known about plant circadian oscillators, in spite of how important they are to sessile
plants, which require accurate timekeepers that enable the plants to respond to their …

Reciprocal Regulation Between TOC1 and LHY/CCA1 Within the Arabidopsis Circadian Clock

D Alabadı́, T Oyama, MJ Yanovsky, FG Harmon, P Más… - Science, 2001 - science.org
The interactive regulation between clock genes is central for oscillator function. Here, we
show interactions between the Arabidopsis clock genes LATE ELONGATED HYPOCOTYL …

The clock gene circuit in Arabidopsis includes a repressilator with additional feedback loops

A Pokhilko, AP Fernández, KD Edwards… - Molecular systems …, 2012 - embopress.org
Circadian clocks synchronise biological processes with the day/night cycle, using molecular
mechanisms that include interlocked, transcriptional feedback loops. Recent experiments …

[HTML][HTML] Modelling the widespread effects of TOC1 signalling on the plant circadian clock and its outputs

A Pokhilko, P Mas, AJ Millar - BMC systems biology, 2013 - Springer
Background 24-hour biological clocks are intimately connected to the cellular signalling
network, which complicates the analysis of clock mechanisms. The transcriptional regulator …

Cloning of the Arabidopsis Clock Gene TOC1, an Autoregulatory Response Regulator Homolog

C Strayer, T Oyama, TF Schultz, R Raman, DE Somers… - Science, 2000 - science.org
The toc1 mutation causes shortened circadian rhythms in light-grown Arabidopsis plants.
Here, we report the same toc1 effect in the absence of light input to the clock. We also show …

Dual role of TOC1 in the control of circadian and photomorphogenic responses in Arabidopsis

P Más, D Alabadí, MJ Yanovsky, T Oyama… - The Plant …, 2003 - academic.oup.com
To examine the role of the TOC1 (TIMING OF CAB EXPRESSION1) gene in the Arabidopsis
circadian system, we generated a series of transgenic plants expressing a gradation in …