Fluctuation of nucleic acid expression and ultrasensitive and specific detection of these
variations in expression is a crucial subject in molecular medicine and clinical theranostics …

Accurate and quantitative analysis of microRNA (miRNA) expression is critical for the
diagnostics and theranostics of a disease. Herein, a proof-of-concept of a colorimetric …

MicroRNA (miRNA) sensing strategies employing rolling circle amplification (RCA) coupled
with the hairpin DNA (HD) probe–mediated FRET assay have shown promise, but achieving …

MicroRNAs (miRNAs) are closely associated with human disease occurrence, including
cancers, diabetes, inflammation, heart diseases, and viral infections, and their rapid and …

MicroRNAs (miRNAs) are found in extremely low concentrations in cells, so highly sensitive
quantitation is a great challenge. Herein, a simple dual-amplification strategy involving …

By using the allosteric hairpin DNA switch, a novel assay for the detection of microRNA
(miRNA) let-7a via a hybridization chain reaction (HCR) was introduced. Briefly, the hairpin …

Monitoring intracellular miRNA levels is essential for early cancer diagnosis. However, it
remains challenging to analyze miRNAs at the cellular level with high accuracy, high …

The detection of miRNA in cells is difficult owing to its substantially low cellular content.
Therefore, developing a highly sensitive sensor to detect cellular miRNA remains a …

MicroRNAs (miRNA) involve in regulating different physiological processes whose
dysregulation is associated with a wide range of diseases including cancers, diabetes and …

In this study, a simple, label-free, and enzyme-free colorimetric biosensor has been
developed for amplified detection of let-7a microRNA (miRNA) on the basis of dual signal …