Long noncoding RNAs control the modulation of immune checkpoint molecules in cancer

S Xu, Q Wang, Y Kang, J Liu, Y Yin, L Liu, H Wu… - Cancer immunology …, 2020 - AACR
Long noncoding RNAs (lncRNA) that are associated with immune checkpoints have not
been identified, and the mechanism by which such lncRNAs might regulate the expression …

[HTML][HTML] Identifying immune checkpoint-related lncRNA biomarkers for immunotherapy response and prognosis in cancers

Y Gao, X Wang, L Dong, C Qu, Q Lu, P Wang, M Xin… - Scientific Data, 2023 - nature.com
Long non-coding RNAs (lncRNAs) could modulate expression of immune checkpoints
(ICPs) in tumor-immune. However, precise functions in immunity and potential for predicting …

The role of LncRNAs in tumor immunotherapy

X Pan, C Li, J Feng - Cancer cell international, 2023 - Springer
Cancer immunotherapy is a major breakthrough in the history of tumor therapy in the last
decade. Immune checkpoint inhibitors blocking CTLA-4/B7 or PD-1/PD-L1 pathways have …

Long noncoding RNA loss in immune suppression in cancer

Q Hu, SD Egranov, C Lin, L Yang - Pharmacology & therapeutics, 2020 - Elsevier
Long noncoding RNAs (lncRNAs) have multiple functions in the regulation of cellular
homeostasis. In recent years, numerous studies have shown that tumor-associated lncRNAs …

The landscape of immune checkpoint-related long non-coding RNAs core regulatory circuitry reveals implications for immunoregulation and immunotherapy …

C Qu, H Cui, S Xiao, L Dong, Q Lu, L Zhang… - Communications …, 2024 - nature.com
Long non-coding RNAs (lncRNAs) could modulate expression of immune checkpoints
(ICPs) by cooperating with immunity genes in tumor immunization. However, precise …

Cancer‐derived non‐coding RNAs endow tumor microenvironment with immunosuppressive properties

T Hu, R Shi, Y Gu, H Zhou, Y Fang, T Xu… - Wiley …, 2024 - Wiley Online Library
Non‐coding RNAs (ncRNAs) have attracted extensive attention due to their vital roles in
tumorigenesis and progression, especially in the immunotherapy resistance. Tumor …

The role of NcRNAs to regulate immune checkpoints in cancer

Y Jiang, L Zhao, Y Wu, S Deng, P Cao, X Lei… - Frontiers in …, 2022 - frontiersin.org
At present, the incidence of cancer is becoming more and more common, but its treatment
has always been a problem. Although a small number of cancers can be treated, the …

Immune‐related long noncoding RNA signature for predicting survival and immune checkpoint blockade in hepatocellular carcinoma

Y Zhang, L Zhang, Y Xu, X Wu… - Journal of cellular …, 2020 - Wiley Online Library
Long noncoding RNAs (lncRNAs) show multiple functions, including immune response.
Recently, the immune‐related lncRNAs have been reported in some cancers. We first …

An Overview of the Immune Modulatory Properties of Long Non-Coding RNAs and Their Potential Use as Therapeutic Targets in Cancer

M Martinez-Castillo, A M. Elsayed, G López-Berestein… - Non-coding RNA, 2023 - mdpi.com
Long non-coding RNAs (lncRNAs) play pivotal roles in regulating immune responses,
immune cell differentiation, activation, and inflammatory processes. In cancer, they are …

The role of long non-coding RNAs in immunotherapy resistance

Y Zhou, Y Zhu, Y Xie, X Ma - Frontiers in oncology, 2019 - frontiersin.org
T-cell-based immunotherapies, particularly immune checkpoint inhibitors, are promising
treatments for various cancers. However, a large subset of patients develop primary or …