Large-scale production of magnetosomes by chemostat culture of Magnetospirillum gryphiswaldense at high cell density

Y Liu, GR Li, FF Guo, W Jiang, Y Li, LJ Li - Microbial cell factories, 2010 - Springer
Background Magnetotactic bacteria have long intrigued researchers because they
synthesize intracellular nano-scale (40-100 nm) magnetic particles composed of Fe 3 O 4 …

[HTML][HTML] High-yield growth and magnetosome formation by Magnetospirillum gryphiswaldense MSR-1 in an oxygen-controlled fermentor supplied solely with air

JB Sun, F Zhao, T Tang, W Jiang, J Tian, Y Li… - Applied microbiology and …, 2008 - Springer
Magnetotactic bacteria are difficult to grow under defined conditions in culture, which has
presented a major obstacle to commercial application of magnetosomes. We studied the …

A key time point for cell growth and magnetosome synthesis of Magnetospirillum gryphiswaldense based on real-time analysis of physiological factors

J Yang, S Li, X Huang, T Tang, W Jiang… - Frontiers in …, 2013 - frontiersin.org
Pure culture of magnetotactic bacteria with high magnetosome yield has been achieved for
only a few strains. The major obstacles involve the nutritional requirements and culture …

An automated oxystat fermentation regime for microoxic cultivation of Magnetospirillum gryphiswaldense

CN Riese, R Uebe, S Rosenfeldt, AS Schenk… - Microbial Cell …, 2020 - Springer
Background Magnetosomes produced by magnetotactic bacteria represent magnetic
nanoparticles with unprecedented characteristics. However, their use in many …

Semicontinuous culture of Magnetospirillum gryphiswaldense MSR-1 cells in an autofermentor by nutrient-balanced and isosmotic feeding strategies

Y Zhang, X Zhang, W Jiang, Y Li… - Applied and environmental …, 2011 - Am Soc Microbiol
An improved strategy was developed for the high-density culture of Magnetospirillum
gryphiswaldense strain MSR-1 and large-scale magnetosome production in both 7.5-and 42 …

A Method for Producing Highly Pure Magnetosomes in Large Quantity for Medical Applications Using Magnetospirillum gryphiswaldense MSR-1 Magnetotactic …

C Berny, R Le Fèvre, F Guyot, K Blondeau… - … in bioengineering and …, 2020 - frontiersin.org
We report the synthesis in large quantity of highly pure magnetosomes for medical
applications. For that, magnetosomes are produced by MSR-1 Magnetospirillum …

Influence of the bacterial growth phase on the magnetic properties of magnetosomes synthesized by Magnetospirillum gryphiswaldense

L Marcano, A García-Prieto, D Muñoz… - … et Biophysica Acta (BBA …, 2017 - Elsevier
Background: The magnetosome biosynthesis is a genetically controlled process but the
physical properties of the magnetosomes can be slightly tuned by modifying the bacterial …

Improved methods for mass production of magnetosomes and applications: a review

A Basit, J Wang, F Guo, W Niu, W Jiang - Microbial Cell Factories, 2020 - Springer
Magnetotactic bacteria have the unique ability to synthesize magnetosomes (nano-sized
magnetite or greigite crystals arranged in chain-like structures) in a variety of shapes and …

Overproduction of magnetosomes by genomic amplification of biosynthesis-related gene clusters in a magnetotactic bacterium

A Lohße, I Kolinko, O Raschdorf, R Uebe… - Applied and …, 2016 - Am Soc Microbiol
Magnetotactic bacteria biosynthesize specific organelles, the magnetosomes, which are
membrane-enclosed crystals of a magnetic iron mineral that are aligned in a linear chain …

[HTML][HTML] Development of a simple intensified fermentation strategy for growth of Magnetospirillum gryphiswaldense MSR-1: physiological responses to changing …

A Fernández-Castané, H Li, ORT Thomas… - New biotechnology, 2018 - Elsevier
The development of a simple pH-stat fed-batch fermentation strategy for the production of
Magnetospirillum gryphiswaldense MSR-1 and magnetosomes (nanoscale magnetic …