Peroxisome proliferator activated receptor alpha (PPAR-α) belongs to the family of ligand-
regulated nuclear receptors (PPARs). These receptors after heterodimerization with retinoid …

Peroxisome proliferator-activated receptors (PPARα,-β/δ and-γ) are lipid-activated
transcription factors. Synthetic PPARα and PPARγ ligands have neuroprotective properties …

Alzheimer's disease is a complex neurodegenerative disorder, with aging, genetic and
environmental factors contributing to its development and progression. The complexity of …

Peroxisome proliferator-activated receptor (PPAR) β/δ belongs to the family of hormone and
lipid-activated nuclear receptors, which are involved in metabolism of long-chain fatty acids …

Over 25 years have passed since peroxisome proliferators‐activated receptors (PPARs),
were first described. Like other members of the nuclear receptors superfamily, PPARs have …

peroxisome proliferator‐activated receptors (PPARs) are nuclear receptors acting as lipid
sensors. Besides its metabolic activity in peripheral organs, the PPAR beta/delta isotype is …

As the growth of the aging population continues to accelerate globally, increased
prevalence of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's …

Diseases of the central nervous system present a challenge for the development of new
therapeutic agents. Nuclear receptors are ligand-activated transcription factors that have …

Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors and they serve to
be a promising therapeutic target for several neurodegenerative disorders, which includes …

The peroxisome proliferator-activated receptor gamma (PPARγ) is a ligand-activated
transcriptional factor that belongs to the nuclear hormone receptor superfamily. PPARγ was …