[HTML][HTML] Anti-apoptotic effects of carotenoids in neurodegeneration

HA Park, MM Hayden, S Bannerman, J Jansen… - Molecules, 2020 - mdpi.com
Apoptosis, programmed cell death type I, is a critical part of neurodegeneration in cerebral
ischemia, Parkinson's, and Alzheimer's disease. Apoptosis begins with activation of pro …

The neuroprotective potential of carotenoids in vitro and in vivo

J Manochkumar, CGP Doss, HR El-Seedi, T Efferth… - Phytomedicine, 2021 - Elsevier
Background Despite advances in research on neurodegenerative diseases, the
pathogenesis and treatment response of neurodegenerative diseases remain unclear …

Recent advances in studies on the therapeutic potential of dietary carotenoids in neurodegenerative diseases

KS Cho, M Shin, S Kim, SB Lee - Oxidative medicine and …, 2018 - Wiley Online Library
Carotenoids, symmetrical tetraterpenes with a linear C40 hydrocarbon backbone, are
natural pigment molecules produced by plants, algae, and fungi. Carotenoids have …

Modulation of apoptotic signalling by carotenoids in cancer cells

P Palozza, S Serini, F Di Nicuolo, G Calviello - Archives of Biochemistry …, 2004 - Elsevier
There is a growing body of literature on the role of β-carotene and other carotenoids in
human chronic diseases, including cancer. While epidemiological evidence shows that a …

[HTML][HTML] Therapeutic promise of carotenoids as antioxidants and anti-inflammatory agents in neurodegenerative disorders

MT Kabir, MH Rahman, M Shah, MR Jamiruddin… - Biomedicine & …, 2022 - Elsevier
Abstract Neurodegenerative disorders (NDs) including Alzheimer's disease, Parkinson's
disease, amyotrophic lateral sclerosis, Huntington's disease, and multiple sclerosis have …

[HTML][HTML] Pro-oxidant actions of carotenoids in triggering apoptosis of cancer cells: A review of emerging evidence

J Shin, MH Song, JW Oh, YS Keum, RK Saini - Antioxidants, 2020 - mdpi.com
Carotenoids are well known for their potent antioxidant function in the cellular system.
However, in cancer cells with an innately high level of intracellular reactive oxygen species …

[HTML][HTML] Carotenoids in Cancer Apoptosis—The Road from Bench to Bedside and Back

L Koklesova, A Liskova, M Samec, C Buhrmann… - Cancers, 2020 - mdpi.com
An incidence and mortality of cancer are rapidly growing worldwide, especially due to
heterogeneous character of the disease that is associated with irreversible impairment of …

Carotenoids induce apoptosis in the T-lymphoblast cell line Jurkat E6. 1

K Müller, KLH Carpenter, IR Challis… - Free radical …, 2002 - Taylor & Francis
Epidemiologically, a high-carotenoid intake via a fruit-and vegetable-rich diet is associated
with a decreased risk of various forms of cancer. The mechanisms by which carotenoids …

[HTML][HTML] Astaxanthin as a potential neuroprotective agent for neurological diseases

H Wu, H Niu, A Shao, C Wu, BJ Dixon, J Zhang, S Yang… - Marine drugs, 2015 - mdpi.com
Neurological diseases, which consist of acute injuries and chronic neurodegeneration, are
the leading causes of human death and disability. However, the pathophysiology of these …

Carotenoids and Alzheimer's disease: an insight into therapeutic role of retinoids in animal models

M Obulesu, MR Dowlathabad… - Neurochemistry …, 2011 - Elsevier
Carotenoids play a pivotal role in prevention of many degenerative diseases mediated by
oxidative stress including neurodegenerative diseases like Alzheimer's Disease (AD). The …