Objective: Studying the effect of multiple dietary strategies on mitochondrial activity of aged
rats. Background: Healthy aging may be achieved by intermittent fasting, caloric restriction or …

Objective: Studying the effect of multiple dietary strategies on mitochondrial activity of aged
rats. Background: Healthy aging may be achieved by intermittent fasting (IF), caloric …

Declines in mitochondrial mass are thought to be a hallmark of mammalian aging, and a
ketogenic diet (KD) may prevent the age-related decreases in mitochondrial content. The …

Dysregulation of mitochondrial energy metabolism is a major hallmark of mammalian aging.
Calorie restriction (CR) has been shown to effectively increase lifespan and is associated …

Long-term intake of high-energy diet can lead to decreased insulin sensitivity and even
insulin resistance, eventually leading to diabetes. Diabetes often occurs in middle-aged and …

The effect of a ketogenic diet (KD) on middle aged female mice is poorly understood as most
of this work have been conducted in young female mice or diseased models. We have …

Age associated neurodegenerative changes are acknowledged to play a causative role in a
majority of neurological diseases that accompany aging in organisms. To alleviate the …

Background Chronic and degenerative diseases are closely related to modern lifestyles that
tend to be deficient in physical activity but excessive in food intake. One method used to …

Background. Ketogenic diet has been used as supportive therapy in a range of conditions
including epilepsy, diabetes mellitus, and cancer. Objective. This study aimed to investigate …

Calorie restriction (CR) is the strategy that has demonstrated a significant impact on slowing
the biological rate of aging and increasing both average and maximum longevity in a variety …