Effect of the combination of different therapies on oxidative stress in the experimental model of multiple sclerosis

BM Escribano, A Muñoz-Jurado, E Luque, A Galván… - Neuroscience, 2023 - Elsevier
Oxidative stress is heavily involved in several pathological features of Multiple Sclerosis
(MS), such as myelin destruction, axonal degeneration, and inflammation. Different …

The role of oxidative stress in the pathogenesis of multiple sclerosis: the need for effective antioxidant therapy

Y Gilgun-Sherki, E Melamed, D Offen - Journal of neurology, 2004 - Springer
Accumulating data indicate that oxidative stress (OS) plays a major role in the pathogenesis
of multiple sclerosis (MS). Reactive oxygen species (ROS), leading to OS, generated in …

New insights into the role of oxidative stress mechanisms in the pathophysiology and treatment of multiple sclerosis

B Adamczyk, M Adamczyk-Sowa - Oxidative medicine and …, 2016 - Wiley Online Library
Multiple sclerosis (MS) is a multifactorial disease of the central nervous system (CNS)
characterized by an inflammatory process and demyelination. The etiology of the disease is …

Oxidative stress in multiple sclerosis

E Miller, M Mrowicka, K Zołyński… - Polski Merkuriusz …, 2009 - europepmc.org
Accumulating data indicate that oxidative stress (OS) plays a major role in the pathogenesis
of multiple sclerosis (MS). Reactive oxygen species (ROS), leading to OS, generated in …

Oxidative stress and excitotoxicity: a therapeutic issue in multiple sclerosis?

RE Gonsette - Multiple Sclerosis Journal, 2008 - journals.sagepub.com
There is increasing evidence that multiple sclerosis (MS) is not only characterized by
immune mediated inflammatory reactions but also by neurodegenerative processes. In …

Antioxidant therapy in multiple sclerosis

A Mirshafiey, M Mohsenzadegan - Immunopharmacology and …, 2009 - Taylor & Francis
Reactive oxygen species (ROS) play an important role in various events underlying multiple
sclerosis pathology. In the initial phase of lesion formation, ROS are known to mediate the …

Oxidative stress in patients with multiple sclerosis.

C Syburra, S Passi - Ukrains' kyi Biokhimichnyi Zhurnal (1999), 1999 - europepmc.org
It is well known that brain and nervous system cells are prone to oxidative damage because
of their relatively low content of antioxidants, especially enzymatic ones, and of the high …

The multiple sclerosis modulatory potential of natural multi-targeting antioxidants

P Theodosis-Nobelos, EA Rekka - Molecules, 2022 - mdpi.com
Multiple sclerosis (MS) is a complex neurodegenerative disease. Although its pathogenesis
is rather vague in some aspects, it is well known to be an inflammatory process …

Antioxidants in multiple sclerosis: do they have a role in therapy?

NG Carlson, JW Rose - CNS drugs, 2006 - Springer
Multiple sclerosis (MS) is an immune-mediated disease, with inflammation and
neurodegeneration contributing to neuronal demyelination and axonal injury. Current …

Multiple sclerosis and oxidative stress—a clinical perspective

MS Kostic, JS Rajkovic, MSP Floranovic, ID Dimov… - Neurochemical …, 2013 - Springer
Multiple Sclerosis (MS) has been traditionally considered to be a chronic inflammatory
disease of central nervous system (CNS), resulting in demyelization and clinical …