Advances in our understanding of brain mechanisms for the hypoxic ventilatory response,
coordinated changes in blood pressure, and the long-term consequences of chronic …

The carotid body is the primary peripheral chemoreceptor in the body, and critical for
respiration and cardiovascular adjustments during hypoxia. Yet considerable evidence now …

Control of respiration provides a powerful voluntary portal to entrain and modulate central
autonomic networks. Slowing and deepening breathing as a relaxation technique has …

Carotid bodies are the principal sensory organs for detecting changes in arterial blood
oxygen concentration, and the carotid body chemoreflex is a major regulator of the …

Maintenance of homeostasis in the respiratory and cardiovascular systems depends on
reflexes that are initiated at specialized peripheral chemoreceptors that sense changes in …

The carotid body (CB) is a prototypical acute oxygen (O2)‐sensing organ that mediates
reflex hyperventilation and increased cardiac output in response to hypoxaemia. CB …

Exposure to hypoxia elicits an immediate increase in ventilation in order to face the tissue
oxygen deficit. The acute response to hypoxia develops gradually over several days despite …

Increasing data support a connection between obstructive sleep apnea (OSA) and cognitive
impairment but a causal link has yet to be established. Although neuronal loss has been …

New Findings What is the topic of this review? This article presents emerging evidence for
heightened carotid body chemoreflex activity as a major driver of sympathetic activation and …

The phase-dependent plasticity of carotid chemoafferent signaling was studied with
electrical stimulation of a carotid sinus nerve during either inspiration or expiration in …