Mucositis as a biological process: a new hypothesis for the development of chemotherapy-induced stomatotoxicity

ST Sonis - Oral oncology, 1998 - Elsevier
Mucositis induced by antineoplastic drugs is an important, dose-limiting and costly side
effect of cancer therapy. The ulcerative lesions which result are frequent systemic portals of …

An animal model for mucositis induced by cancer chemotherapy

ST Sonis, C Tracey, G Shklar, J Jenson… - Oral surgery, oral …, 1990 - Elsevier
Mucositis induced by chemotherapy is a painful and often dose-limiting side effect of cancer
therapy. Furthermore, loss of the integrity of the oral epithelium often provides a microbial …

Prevention and treatment of oral mucositis following cancer chemotherapy.

JD Wilkes - Seminars in oncology, 1998 - europepmc.org
The administration of many chemotherapy regimens may be complicated by toxicities that
limit clinicians' abilities to deliver the most effective doses of active agents. Oral mucositis …

Chemotherapy-induced oral mucositis: prevention and management

JJ Knox, ALV Puodziunas, R Feld - Drugs & aging, 2000 - Springer
Oral mucositis is a frequent and potentially severe complication of chemotherapy which has
a considerable impact on patient quality of life. While the management of other …

Chemotherapy-induced and/or radiation therapy-induced oral mucositis-complicating the treatment of cancer

MUR Naidu, GV Ramana, PU Rani, A Suman, P Roy - Neoplasia, 2004 - Elsevier
The term mucositis is coined to describe the adverse effects of radiation and chemotherapy
treatments. Mucositis is one of the most common adverse reactions encountered in radiation …

Oral mucositis complicating chemotherapy and/or radiotherapy: options for prevention and treatment

WJ Köstler, M Hejna, C Wenzel… - CA: a cancer journal for …, 2001 - Wiley Online Library
Chemotherapy‐and radiotherapy‐induced oral mucositis represents a therapeutic challenge
frequently encountered in cancer patients. This side effect causes significant morbidity and …

Perspectives on cancer therapy‐induced mucosal injury: pathogenesis, measurement, epidemiology, and consequences for patients

ST Sonis, LS Elting, D Keefe… - … Journal of the …, 2004 - Wiley Online Library
BACKGROUND A frequent complication of anticancer treatment, oral and gastrointestinal
(GI) mucositis, threatens the effectiveness of therapy because it leads to dose reductions …

Cancer therapy and oral mucositis: an appraisal of drug prophylaxis

CJ Verdi - Drug safety, 1993 - Springer
Oral mucositis as a consequence of cytotoxic therapy is a major cause of morbidity in cancer
patients. Cancer therapy-induced tissue damage leading to mucositis can occur through …

Prevention and management of oral mucositis induced by antineoplastic therapy.

S Sonis, J Clark - Oncology (Williston Park, NY), 1991 - europepmc.org
Oral complications almost always occur as a consequence of treatment for head and neck
cancer. In addition, approximately 40% of patients with nonhead and neck malignancies …

Risk factors for ulcerative oral mucositis in cancer patients: unanswered questions

A Barasch, DE Peterson - Oral oncology, 2003 - Elsevier
A multitude of laboratory and clinical research studies of ulcerative oral mucositis induced by
cytotoxic cancer therapies have been reported during the past decade. However, a …