Fluconazole Resistance and Virulence in In Vitro Induced-Fluconazole Resistant Strains and in Clinical Fluconazole Resistant Strain of Cryptococcus deuterogattii

S Bertout, L Laroche, F Roger, D Krasteva… - Pathogens, 2023 - mdpi.com
Neuromeningeal cryptococcosis is a life-threatening infection of the central nervous system,
caused by encapsulated yeast belonging to the Cryptococcus neoformans and …

Dynamic and Heterogeneous Mutations to Fluconazole Resistance in Cryptococcus neoformans

J Xu, C Onyewu, HJ Yoell, RY Ali… - Antimicrobial Agents …, 2001 - Am Soc Microbiol
Infections with the human pathogenic basidiomycetous yeast Cryptococcus neoformans are
often treated with fluconazole. Resistance to this antifungal agent has been reported. This …

Characterization of Heteroresistance to Fluconazole among Clinical Isolates of Cryptococcus neoformans

T Yamazumi, MA Pfaller, SA Messer… - Journal of clinical …, 2003 - Am Soc Microbiol
Strains of Cryptococcus neoformans expressing heteroresistance to fluconazole have been
described previously. The present study was conducted to investigate the prevalence of …

Heteroresistance of Cryptococcus gattii to Fluconazole

A Varma, KJ Kwon-Chung - Antimicrobial Agents and …, 2010 - Am Soc Microbiol
We analyzed 71 clinical and environmental Cryptococcus gattii strains that had been
isolated before or after the advent of azole antifungals to determine their level of …

Heteroresistance to Fluconazole and Voriconazole inCryptococcus neoformans

P Mondon, R Petter, G Amalfitano… - Antimicrobial Agents …, 1999 - Am Soc Microbiol
Cryptococcus neoformans isolates that exhibited unusual patterns of resistance to
fluconazole and voriconazole were isolated from seven isolates from two different …

Fluconazole tolerance in clinical isolates of Cryptococcus neoformans

K Venkateswarlu, M Taylor, NJ Manning… - Antimicrobial agents …, 1997 - Am Soc Microbiol
Eleven isolates of Cryptococcus neoformans were investigated to determine the biochemical
basis of their tolerance to fluconazole. The MICs of fluconazole for three isolates with low …

Impact of Resistance to Fluconazole on Virulence and Morphological Aspects of Cryptococcus neoformans and Cryptococcus gattii Isolates

SA Rossi, N Trevijano-Contador, L Scorzoni… - Frontiers in …, 2016 - frontiersin.org
Cryptococcus sp. are responsible for around 1 million cases of meningitis every year.
Fluconazole (FLU) is commonly used in the treatment of cryptococcosis, mainly in …

In Vitro Susceptibility of the Yeast Pathogen Cryptococcus to Fluconazole and Other Azoles Varies with Molecular Genotype

HS Chong, R Dagg, R Malik, S Chen… - Journal of clinical …, 2010 - Am Soc Microbiol
Cryptococcosis is primarily caused by Cryptococcus neoformans and Cryptococcus gattii.
These two pathogenic species each divide into four distinct molecular genotypes. In this …

Cryptococcus neoformans serotype A and Cryptococcus gattii serotype B isolates differ in their susceptibilities to fluconazole and voriconazole

ZU Khan, HS Randhawa, W Chehadeh… - International journal of …, 2009 - Elsevier
This study presents antifungal susceptibility data for environmental isolates of Cryptococcus
neoformans serotype A (n= 32) and Cryptococcus gattii serotype B (n= 18) to fluconazole …

Heteroresistance to Fluconazol in Clinical and Environmental Brazilian Strains of Cryptococcus neoformans/C. gattii Species Complex

LM Feliciano, SDP Ramos, MW Szeszs… - Current Fungal Infection …, 2017 - Springer
Abstract Purpose of Study To review the literature on heteroresistance to fluconazole (FLC)
and investigate the level of heteroresistance to FLC (LHF), we analyzed 100 clinical and …