Severe acute pancreatitis (AP) is a life-threatening pancreatic inflammatory disease with a
high mortality rate (∼ 40%). Existing pharmaceutical therapies in development or in clinical …

Acute pancreatitis (AP) is a severe life-threatening inflammatory disease showing primary
characteristics of excessive inflammatory response and oxidative stress. Based on the …

Calcium overload, a notable instigator of acute pancreatitis (AP), induces oxidative stress
and an inflammatory cascade, subsequently activating both endogenous and exogenous …

Severe acute pancreatitis (SAP), characterized by pancreatic acinar cell death, currently
lacks effective targeted therapies. Ellagic acid (EA), rich in pomegranate, shows promising …

Acute pancreatitis (AP) is a common and life-threatening digestive disorder. However, its
diagnosis and treatment are still impeded by our limited understanding of its etiology …

Kaempferol (KA), an natural antioxidant of traditional Chinese medicine (TCM), is
extensively used as the primary treatment for inflammatory digestive diseases with impaired …

The timely suppression of inflammatory mediator production and mitigation of their effects on
pancreatic acinar cells are crucial for the successful management of acute pancreatitis. To …

Background Sever acute pancreatitis (SAP) is a critical disease with high mortality, and lack
of clinically available treatments with specificity and effectiveness. Bone marrow derived …

Acute pancreatitis (AP) is a life-threatening inflammatory disease of the pancreas. When AP
occurs, macrophages are recruited and stimulated to pro-inflammatory M1 phenotype …

Severe acute pancreatitis (SAP) is a serious inflammatory disease that is often associated
with high mortality rate. It tends to trigger a cascade of systemic inflammation that causes …