All the events of egg activation in mammalian eggs are triggered physiologically by transient
increases in cytosolic free Ca²⁺ referred to as Ca²⁺ ioscillations. These oscillations are …

Mammalian eggs undergo a prolonged series of low frequency Ca2+ oscillations at
fertilization. These Ca2+ oscillations are the immediate cause of egg activation. The Ca2+ …

Sperm-specific phospholipase C ζ (PLCζ) activates embryo development by triggering
intracellular Ca2+ oscillations in mammalian eggs indistinguishable from those at …

Phospholipase C-zeta (PLCζ) is a sperm-specific protein believed to cause Ca2+
oscillations and egg activation during mammalian fertilization. PLCζ is very similar to the …

Inositol 1, 4, 5-trisphosphate generated by the action of a phospholipase C (PLC) mediates
release of intracellular Ca2+ that is essential for sperm-induced activation of mammalian …

Upon fertilisation by sperm, mammalian eggs are activated by a series of intracellular Ca2+
oscillations that are essential for embryo development. The mechanism by which sperm …

Sperm PLCζ (phospholipase Cζ) is a distinct phosphoinositide-specific PLC isoform that is
proposed to be the physiological trigger of egg activation and embryo development at …

A series of intracellular oscillations in the free cytosolic Ca2+ concentration is responsible
for activating mammalian eggs at fertilization, thus initiating embryo development. It has …

Egg activation is the first step of embryonic development and in mammals is triggered by a
series of cytoplasmic calcium (Ca2+) oscillations. Sperm–egg fusion initiates these Ca2+ …

Egg activation is the earliest step of embryonic development following mammalian
fertilization and is triggered by a characteristic series of cytoplasmic calcium (Ca 2+) …