▪ Abstract Fifteen years ago, we had a model of peroxisome biogenesis that involved growth
and division of preexisting peroxisomes. Today, thanks to genetically tractable model …

Investigations of peroxisome biogenesis in diverse organisms reveal new details of this
unique process and its evolutionary conservation. Interactions among soluble receptors and …

We describe the isolation and characterization of a homologous pair of proteins, Pex25p
(YPL112c) and Pex27p (YOR193w), whose C-termini are similar to the entire Pex11p. All …

Peroxisomes are ubiquitous subcellular organelles, which multiply by growth and division
but can also form de novo via the endoplasmic reticulum. Growth and division of …

Peroxisomes are ubiquitous organelles that proliferate under different physiological
conditions and can form de novo in cells that lack them. The endoplasmic reticulum (ER) has …

Rat cDNA encoding a 372-amino-acid peroxin was isolated, primarily by functional
complementation screening, using a peroxisome-deficient Chinese hamster ovary cell …

Peroxisome assembly in mammals requires more than 15 genes. Two isoforms of the
peroxisome targeting signal type 1 (PTS1) receptor, Pex5pS and Pex5pL, are identified in …

Peroxisomes are independent organelles found in virtually all eukaryotic cells. Genetic
studies have identified more than 20 PEX genes that are required for peroxisome …

Peroxisome is an organelle conserved in almost all eukaryotic cells with a variety of
functions in cellular metabolism, including fatty acid β-oxidation, synthesis of ether …

Peroxisomes perform a wide variety of metabolic processes in eukaryotic organisms.
Mutations that affect peroxisome function or formation have profound phenotypic …