[HTML][HTML] Glucocorticoids—all-rounders tackling the versatile players of the immune system

C Strehl, L Ehlers, T Gaber, F Buttgereit - Frontiers in immunology, 2019 - frontiersin.org
Glucocorticoids regulate fundamental processes of the human body and control cellular
functions such as cell metabolism, growth, differentiation, and apoptosis. Moreover …

Immune regulation by glucocorticoids

DW Cain, JA Cidlowski - Nature Reviews Immunology, 2017 - nature.com
Endogenous glucocorticoids are crucial to various physiological processes, including
metabolism, development and inflammation. Since 1948, synthetic glucocorticoids have …

The kaleidoscope of glucorticoid effects on immune system

M Zen, M Canova, C Campana, S Bettio, L Nalotto… - Autoimmunity …, 2011 - Elsevier
Glucocorticoids (GCs) are potent anti-inflammatory and immunosuppressive agents which
exert multiple effects on immune cell functions. Although their use dates back 60years, their …

Effects of glucocorticoids in the immune system

E Oppong, ACB Cato - Glucocorticoid signaling: from molecules to mice to …, 2015 - Springer
Glucocorticoids (GCs) are steroid hormones with widespread effects. They control
intermediate metabolism by stimulating gluconeogenesis in the liver, mobilize amino acids …

Overview of the actions of glucocorticoids on the immune response: a good model to characterize new pathways of immunosuppression for new treatment strategies

D Franchimont - Annals of the New York Academy of Sciences, 2004 - Wiley Online Library
Glucocorticoids have been used for over 50 years in the treatment of inflammatory and
autoimmune diseases and in preventing graft rejection. Today, knowledge of their …

Minireview: Glucocorticoids in autoimmunity: unexpected targets and mechanisms

JR Flammer, I Rogatsky - Molecular endocrinology, 2011 - academic.oup.com
For decades, natural and synthetic glucocorticoids (GC) have been among the most
commonly prescribed classes of immunomodulatory drugs. Their unsurpassed …

Optimized glucocorticoid therapy: teaching old drugs new tricks

C Strehl, F Buttgereit - Molecular and cellular endocrinology, 2013 - Elsevier
Glucocorticoids (GCs) are commonly used in the treatment of a wide range of rheumatic and
other inflammatory diseases. They exert their potent anti-inflammatory and …

Glucocorticoids and immune function: unknown dimensions and new frontiers

T Wilckens, R De Rijk - Immunology today, 1997 - cell.com
Despite the importance of glucocorticoids (GCs) to modern medicine, the physiological role
of endogenous corticostcroids in immunomodulation is poorly understood. This article …

[HTML][HTML] Regulatory and mechanistic actions of glucocorticoids on T and inflammatory cells

AC Liberman, ML Budzinski, C Sokn… - Frontiers in …, 2018 - frontiersin.org
Glucocorticoids (GCs) play an important role in regulating the inflammatory and immune
response and have been used since decades to treat various inflammatory and autoimmune …

Defining the role of glucocorticoids in inflammation

S Ronchetti, G Migliorati, S Bruscoli… - Clinical Science, 2018 - portlandpress.com
An established body of knowledge and clinical practice has argued in favor of the use of
glucocorticoids in various chronic inflammatory and autoimmune diseases. However, the …