The Streptococcus pneumoniae adhesin PsrP binds to Keratin 10 on lung cells

P Shivshankar, C Sanchez, LF Rose… - Molecular …, 2009 - Wiley Online Library
Pneumococcal serine‐rich repeat protein (PsrP) is a pathogenicity island‐encoded adhesin
that mediates attachment to lung cells. It is a member of the serine‐rich repeat protein family …

The Pneumococcal Serine-Rich Repeat Protein Is an Intra-Species Bacterial Adhesin That Promotes Bacterial Aggregation In Vivo and in Biofilms

CJ Sanchez, P Shivshankar, K Stol… - PLoS …, 2010 - journals.plos.org
The Pneumococcal serine-rich repeat protein (PsrP) is a pathogenicity island encoded
adhesin that has been positively correlated with the ability of Streptococcus pneumoniae to …

Antibodies against PsrP, a Novel Streptococcus pneumoniae Adhesin, Block Adhesion and Protect Mice against Pneumococcal Challenge

L Rose, P Shivshankar, E Hinojosa… - The Journal of …, 2008 - academic.oup.com
Pneumococcal serine-rich repeat protein (PsrP) is a putative adhesin encoded in the
Streptococcus pneumoniae pathogenicity island psrP-secY2A2. Challenge of mice with …

Cloning and nucleotide sequence analysis of psaA, the Streptococcus pneumoniae gene encoding a 37-kilodalton protein homologous to previously reported …

JS Sampson, SP O'Connor, AR Stinson… - Infection and …, 1994 - Am Soc Microbiol
Gene psaA, which encodes the Streptococcus pneumoniae 37-kDa protein, was cloned in
Escherichia coli, and its complete nucleotide sequence was determined. Analysis of the …

Sequence heterogeneity of PsaA, a 37-kilodalton putative adhesin essential for virulence of Streptococcus pneumoniae

AM Berry, JC Paton - Infection and immunity, 1996 - Am Soc Microbiol
psaA encodes a 37-kDa putative pneumococcal surface adhesin. Although its complete
nucleotide sequence has been determined, its contribution to the pathogenicity of …

PspK of Streptococcus pneumoniae increases adherence to epithelial cells and enhances nasopharyngeal colonization

LE Keller, CV Jones, JA Thornton… - Infection and …, 2013 - Am Soc Microbiol
Streptococcus pneumoniae (the pneumococcus) colonizes the human nasopharynx and can
cause invasive disease aided by the pneumococcal capsule. Group II nontypeable S …

The BR domain of PsrP interacts with extracellular DNA to promote bacterial aggregation; structural insights into pneumococcal biofilm formation

T Schulte, C Mikaelsson, A Beaussart, A Kikhney… - Scientific Reports, 2016 - nature.com
The major human pathogen Streptococcus pneumoniae is a leading cause of disease and
death worldwide. Pneumococcal biofilm formation within the nasopharynx leads to long-term …

Characterization of selected strains of pneumococcal surface protein A

MJ Jedrzejas, E Lamani, RS Becker - Journal of Biological Chemistry, 2001 - ASBMB
Several proteins, in addition to the polysaccharide capsule, have recently been implicated in
the full virulence of the Streptococcus pneumoniae bacterial pathogen. One of these novel …

Plasminogen-and fibronectin-binding protein B is involved in the adherence of Streptococcus pneumoniae to human epithelial cells

S Papasergi, M Garibaldi, G Tuscano… - Journal of Biological …, 2010 - ASBMB
Streptococcus pneumoniae is a major cause of morbidity and mortality worldwide. The
ability of this bacterium to adhere to epithelial cells is considered as an essential early step …

PavB is a surface‐exposed adhesin of Streptococcus pneumoniae contributing to nasopharyngeal colonization and airways infections

I Jensch, G Gámez, M Rothe, S Ebert… - Molecular …, 2010 - Wiley Online Library
The genomic analysis of Streptococcus pneumoniae strains identified the Pneumococcal
adherence and virulence factor B (PavB), whose repetitive sequences, designated …