Therapeutic DNA vaccines for human papillomavirus and associated diseases

MA Cheng, E Farmer, C Huang, J Lin, CF Hung… - Human gene …, 2018 - liebertpub.com
Human papillomavirus (HPV) has long been recognized as the causative agent of cervical
cancer. High-risk HPV types 16 and 18 alone are responsible for over 70% of all cases of …

Therapeutic HPV DNA vaccines

A Monie, SWD Tsen, CF Hung, TC Wu - Expert review of vaccines, 2009 - Taylor & Francis
Human papillomavirus (HPV) has been associated with several human cancers, including
cervical cancer, vulvar cancer, vaginal and anal cancer, and a subset of head and neck …

Therapeutic DNA vaccines against HPV-related malignancies: promising leads from clinical trials

J Tang, M Li, C Zhao, D Shen, L Liu, X Zhang, L Wei - Viruses, 2022 - mdpi.com
In 2014 and 2021, two nucleic-acid vaccine candidates named MAV E2 and VGX-3100
completed phase III clinical trials in Mexico and US, respectively, for patients with human …

Vaccines for HPV-associated diseases

JM Skolnik, MP Morrow - Molecular Aspects of Medicine, 2023 - Elsevier
Human papillomavirus (HPV) infection represents a significant global health concern owing
to its role in the etiology of conditions ranging from benign low-grade lesions to cancers of …

Therapeutic hpv DNA vaccines

K Lin, E Roosinovich, B Ma, CF Hung, TC Wu - Immunologic research, 2010 - Springer
It is now well established that most cervical cancers are causally associated with HPV
infection. This realization has led to efforts to control HPV-associated malignancy through …

Control of HPV infection and related cancer through vaccination

NP Tran, CF Hung, R Roden, TC Wu - Viruses and Human Cancer: From …, 2014 - Springer
Human papillomavirus (HPV), the most common sexually transmitted virus, and its
associated diseases continue to cause significant morbidity and mortality in over 600 million …

[HTML][HTML] DNA vaccines for cervical cancer

CF Huang, A Monie, WH Weng… - American journal of …, 2010 - ncbi.nlm.nih.gov
Human papillomavirus (HPV), particularly type 16, has been associated with more than 99%
of cervical cancers. There are two HPV oncogenic proteins, E6 and E7, which play a major …

Therapeutic vaccine strategies against human papillomavirus

H Khallouf, AK Grabowska, AB Riemer - Vaccines, 2014 - mdpi.com
High-risk types of human papillomavirus (HPV) cause over 500,000 cervical, anogenital and
oropharyngeal cancer cases per year. The transforming potential of HPVs is mediated by …

Prevention of cervical cancer through papillomavirus vaccination

IH Frazer - Nature Reviews Immunology, 2004 - nature.com
A subset of human papillomaviruses (HPVs) promote anogenital malignancy, including
cervical cancer, and prevention and treatment strategies that reflect the causal role of HPV …

Enhanced therapeutic effects conferred by an experimental DNA vaccine targeting human papillomavirus-induced tumors

MO Diniz, FAMO Cariri, LRMM Aps… - Human gene …, 2013 - liebertpub.com
Human papillomavirus (HPV) infection is responsible for all cervical cancer cases, other
anogenital cancers, and head and neck tumors. The epidemiological relevance of HPV …