Almost 40 years after the first description of familial combined hyperlipidaemia (FCHL) as a
discrete entity, the genetic and metabolic basis of this prevalent disease has yet to be fully …

Among different types of dyslipidemia, familial combined hyperlipidemia (FCHL) is the most
common genetic disorder, which is characterized by at least two different forms of lipid …

Ongoing basic research provides a steady growth in our knowledge on the genes that are
involved in FCHL as well as their metabolic function (s). This field of research may be …

Familial combined hyperlipidemia (FCHL) is the most common genetic dyslipidemia
disorder which is accompanied by increasing of triglyceride and cholesterol. This disorder is …

Recent progress in genomics has shown that most if not all of the genetic susceptibility to
FCH is polygenic in nature. Future research should include larger cohort studies, with wider …

Familial combined hyperlipidaemia (FCHL) was described in 1973 by three separate groups
as a common familial disorder characterized by multiple lipoprotein phenotypes and an …

Familial combined hyperlipidemia (FCHL) constitutes a substantial risk factor for
atherosclerosis since it is observed in about 20% of coronary heart disease (CHD) patients …

Familial combined hyperlipidemia (FCHL) is a dyslipidemic syndrome prevalent in patients
with coronary artery disease. Other phenotypes that appear to have a kinship with FCHL …

Familial combined hyperlipidaemia (FCHL) is one of the most common hereditary disorders
predisposing to early coronary death. The affected family members have elevations of serum …

Overproduction of VLDL (very-low-density lipoprotein) particles is an important cause of
FCHL (familial combined hyperlipidaemia). It has been shown recently that VLDL production …