Stem cell spheroids are advanced building blocks to produce chondroid. However, the multi-
step operations including spheroids preparation, collection and transfer, the following 3D …

Based on “bottom-up” strategy, cell-laden 3D bioprinting is an important process of
fabricating sophisticated biomimetic structures. Stem cell spheroids possess better …

Bioprinting of most cell-laden hydrogel scaffolds with the required structural integrity,
mechanical modulus, cell adhesion, cell compatibility, and chondrogenic differentiation are …

Cell spheroids are a promising bioprinting building block that can mimic several
physiological conditions in embryonic development. However, it remains challenging to …

Direct injection of chondrocytes in a minimally invasive way has been regarded as the
significantly potential treatment for cartilage repair due to their ability to fill various irregular …

A combination of hydrogels and stem cell spheroids has been used to engineer three-
dimensional (3D) osteochondral tissue, but precise zonal control directing cell fate within the …

Abstract 3D cellular spheroids offer more biomimetic microenvironments than conventional
2D cell culture technologies, which has proven value for many tissue engineering …

Osteochondral (OC) disorders such as osteoarthritis (OA) damage joint cartilage and
subchondral bone tissue. To understand the disease, facilitate drug screening, and advance …

To date, the treatment of articular cartilage lesions remains challenging. A promising
strategy for the development of new regenerative therapies is hybrid bioprinting, combining …

The insufficient pore structure of cell-laden hydrogel scaffolds has limited their application in
various tissue regeneration applications owing to low cell-to-cell/matrix interactions and low …