Implications of serum chloride homeostasis in acute heart failure (from ROSE-AHF)
JL Grodin, JL Sun, KJ Anstrom, HH Chen… - The American journal of …, 2017 - Elsevier
Lower serum chloride (Cl) levels are strongly associated with increased long-term mortality
after admission for acute heart failure (AHF). However, the therapeutic implications of serum …
after admission for acute heart failure (AHF). However, the therapeutic implications of serum …
Prognostic role of serum chloride levels in acute decompensated heart failure
JL Grodin, J Simon, R Hachamovitch, Y Wu… - Journal of the American …, 2015 - jacc.org
Background: Acute decompensated heart failure (ADHF) can be complicated by electrolyte
abnormalities, but the major focus has been concentrated on the clinical significance of …
abnormalities, but the major focus has been concentrated on the clinical significance of …
Hemodynamic factors associated with serum chloride in ambulatory patients with advanced heart failure
JL Grodin, W Mullens, M Dupont, DO Taylor… - International Journal of …, 2018 - Elsevier
Abstract Background Lower serum chloride (Cl) is associated with mortality in heart failure
patients and may be more prognostically relevant than sodium. However, the association of …
patients and may be more prognostically relevant than sodium. However, the association of …
Importance of abnormal chloride homeostasis in stable chronic heart failure
JL Grodin, FH Verbrugge, SG Ellis… - Circulation: Heart …, 2016 - Am Heart Assoc
Background—The aim of this analysis was to determine the long-term prognostic value of
lower serum chloride in patients with stable chronic heart failure. Electrolyte abnormalities …
lower serum chloride in patients with stable chronic heart failure. Electrolyte abnormalities …
Serum chloride as a novel marker for adding prognostic information of mortality in chronic heart failure
Y Zhang, R Peng, X Li, J Yu, X Chen, Z Zhou - Clinica Chimica Acta, 2018 - Elsevier
Background Serum chloride concentrations have clinical significance in the prognosis of
heart failure (HF). Little is known regarding the prognostic value of serum chloride in patients …
heart failure (HF). Little is known regarding the prognostic value of serum chloride in patients …
Prognostic significance of serum chloride level in heart failure patients with preserved ejection fraction
M Seo, T Watanabe, T Yamada, M Yano… - ESC Heart …, 2022 - Wiley Online Library
Aims The prognostic value of serum chloride level has been reported primarily in patients
with heart failure with reduced ejection fraction, and hence, there is limited evidence in …
with heart failure with reduced ejection fraction, and hence, there is limited evidence in …
Trajectory of serum chloride levels during decongestive therapy in acute heart failure
S Kurashima, T Kitai, Y Matsue, K Nogi… - International Journal of …, 2023 - Elsevier
Background Hypochloremia is a risk factor for poor outcomes in patients with acute heart
failure (AHF). However, the changes in serum chloride levels during decongestion therapy …
failure (AHF). However, the changes in serum chloride levels during decongestion therapy …
Serum chloride and sodium interplay in patients with acute myocardial infarction and heart failure with reduced ejection fraction: an analysis from the high-risk …
Background—Serum chloride levels were recently found to be independently associated
with mortality in heart failure (HF). Methods and Results—We investigated the relationship …
with mortality in heart failure (HF). Methods and Results—We investigated the relationship …
Hypochloremia, diuretic resistance, and outcome in patients with acute heart failure
JM Ter Maaten, K Damman, JS Hanberg… - Circulation: Heart …, 2016 - Am Heart Assoc
Background—Chloride plays a role in renal salt sensing, neurohormonal activation, and
regulation of diuretic targets, and hypochloremia predicts mortality in acute heart failure …
regulation of diuretic targets, and hypochloremia predicts mortality in acute heart failure …
Perturbations in serum chloride homeostasis in heart failure with preserved ejection fraction: insights from TOPCAT
JL Grodin, JM Testani, A Pandey… - European journal of …, 2018 - Wiley Online Library
Aims Prior cohorts demonstrating the importance of serum chloride levels in heart failure
either excluded or had partial representation of patients with heart failure with preserved …
either excluded or had partial representation of patients with heart failure with preserved …
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