Simvastatin inhibits PD-L1 via ILF3 to enhance CD8+ T cell-mediated ferroptosis in gastric cancer cells
D Sun, X Cui, W Yang, M Wei, Z Yan, M Zhang, Z Wang… - 2024 - researchsquare.com
Background Immunotherapy is vital in the comprehensive treatment of gastric cancer (GC).
However, the prognosis of GC patients remains unfavorable, necessitating to exploration of …
However, the prognosis of GC patients remains unfavorable, necessitating to exploration of …
Effect of simvastatin on PD-L1 via ILF3 to enhance CD8+ T cell-mediated ferroptosis in gastric cancer cells.
D Sun, W Yu, X Cui - 2024 - ascopubs.org
e16056 Background: Immunotherapy is vital in the comprehensive treatment of gastric
cancer (GC). However, the prognosis of GC patients remains unfavorable, necessitating to …
cancer (GC). However, the prognosis of GC patients remains unfavorable, necessitating to …
[HTML][HTML] Apolipoprotein L3 enhances CD8+ T cell antitumor immunity of colorectal cancer by promoting LDHA-mediated ferroptosis
Y Lv, WT Tang, YQ Xu, WJ Chang… - … Journal of Biological …, 2023 - ncbi.nlm.nih.gov
Aim: Colorectal cancer (CRC) is the leading cause of cancer associated death worldwide
and immune checkpoint blockade therapy only benefit a small set of CRC patients. Tumor …
and immune checkpoint blockade therapy only benefit a small set of CRC patients. Tumor …
[引用][C] 1946P SLC7A9 suppression increases chemosensitivity by inducing ferroptosis via inhibiting cystine transportation in gastric cancer
J Li, H Feng, ZG Zhu, B Liu - Annals of Oncology, 2024 - annalsofoncology.org
Background The aims of the study was to reveal the mechanisms of SLC7A9 regulating
ferroptosis in gastric cancer cells and explore new treatment strategies for gastric cancer …
ferroptosis in gastric cancer cells and explore new treatment strategies for gastric cancer …
Ferroptosis regulator SLC7A11 is a prognostic marker and correlated with PD-L1 and immune cell infiltration in liver hepatocellular carcinoma
Y Liang, S Su, Z Lun, Z Zhong, W Yu, G He… - Frontiers in Molecular …, 2022 - frontiersin.org
Background: Liver hepatocellular carcinoma (LIHC) is a complicated disease with poor
survival and lack of viable treatment options. The roles of ferroptosis and immunotherapy in …
survival and lack of viable treatment options. The roles of ferroptosis and immunotherapy in …
Aberrant expression of KDM1A inhibits ferroptosis of lung cancer cells through up-regulating c-Myc
C Lu, Y Cai, W Liu, B Peng, Q Liang, Y Yan, D Liang… - Scientific Reports, 2022 - nature.com
Ferroptosis is a cell death process caused by metabolic dysfunction with the feature of
aberrant iron accumulation. Emerging studies have identified that ferroptosis is an important …
aberrant iron accumulation. Emerging studies have identified that ferroptosis is an important …
Prognostic value of the ferroptosis-related gene SLC2A3 in gastric cancer and related immune mechanisms
L Lin, R Que, J Wang, Y Zhu, X Liu, R Xu - Frontiers in genetics, 2022 - frontiersin.org
SLC2A3 is a ferroptosis marker engaged in transmembrane glucose transport. However, the
effect of SLC2A3 on the prognosis of patients with cancer remains unclear. This study aimed …
effect of SLC2A3 on the prognosis of patients with cancer remains unclear. This study aimed …
LTBP2 Knockdown Promotes Ferroptosis in Gastric Cancer Cells through p62‐Keap1‐Nrf2 Pathway
TA Wang, ZH Zhou, CM Wang, YZ Qin… - BioMed Research …, 2022 - Wiley Online Library
Gastric cancer (GC) is one of the most common gastrointestinal malignancies. Ferroptosis is
a new type of peroxidation‐driven and iron‐dependent cell death. However, the biological …
a new type of peroxidation‐driven and iron‐dependent cell death. However, the biological …
[PDF][PDF] IL6ST: A Novel Therapeutic Target for Managing and Treating Colorectal Cancer Via Ferroptosis
K Zhao, B He, K Xue, B Cao, K Ren, Y Jin… - Turk J …, 2024 - turkjgastroenterol.org
ABSTRACT Background/Aims: Inflammation is an essential driver of colorectal cancer
(CRC). Identifying phenotypes and targets associated with inflammation and cancer may be …
(CRC). Identifying phenotypes and targets associated with inflammation and cancer may be …
LncRNAs Target Ferroptosis-Related Genes and Impair Activation of CD4+ T Cell in Gastric Cancer
F Yao, Y Zhan, Z Pu, Y Lu, J Chen, J Deng… - Frontiers in cell and …, 2021 - frontiersin.org
Gastric cancer (GC) is a malignant disease of the digestive tract and a life-threatening
disease worldwide. Ferroptosis, an iron-dependent cell death caused by lipid peroxidation …
disease worldwide. Ferroptosis, an iron-dependent cell death caused by lipid peroxidation …