Head and neck cancer (HNC) is an ascending and agressive disease. The search for new
molecular markers is emerging to solve difficulties in diagnosis, risk management, prognosis …

Buccal mucosa squamous cell carcinoma (BMSCC) is the most common oral cancer in
Southeast Asia. Caspase-3, a key molecule in regulating apoptosis, promotes the …

Apoptosis plays a dual role in cancer development and malignancy. The role of apoptosis-
related caspases in cancer remains controversial, particularly in oral tongue squamous cell …

Background Apoptosis is a genetically programmed form of cell death, of which caspases
are the central components. Methods By tissue microarray of 229 cases of oral squamous …

Emerging evidence has indicated that apoptotic cells have a compensatory effect on the
proliferation of neighboring cells. Recent studies have shown that apoptotic tumor cells …

Death receptor 5 (DR5) and caspase-8 are major components in the extrinsic apoptotic
pathway. The alterations of the expression of these proteins during the metastasis of head …

Various studies have evaluated the relationship between Caspase-3 expression and
cancers of digestive tract. However, the prognostic value of Caspase-3 expression remains …

Oral cancer is the most common form of head and neck squamous cell carcinoma (HNSCC)
and most frequently presents as oral squamous cell carcinoma (OSCC), which is associated …

Oral carcinomas are known to have a greater apoptotic index than normal oral epithelium,
evident as shrinking cells with condensed chromatin. In this study, these morphologically …

Objectives: Caspase-3 is one of the most important molecules in the apoptosis cascade, and
the relationship between caspase-3 expression and prognosis has been reported in many …