Background Radical resection is associated with good prognosis among patients with
cT1/T2Nx rectal cancer. However, still some of the patients experienced cancer recurrence …

Background Local excision (LE) is a feasible treatment approach for rectal cancers in stage
pT1 and presents low pathological risk, whereas total mesorectal excision (TME) is a …

Background Radical resection with total mesorectal excision (TME) is the accepted standard
of care for most rectal cancers. However, T1 rectal cancers may be at low risk for metastases …

Background Few reports have evaluated the long-term outcomes of pathological T1 (pT1)
lower rectal cancer (LRC), perhaps because pT1 LRC is classified as TNM stage I if lymph …

Abstract Background Due to the Total Mesorectal Excision (TME) surgery made a good local
control, the role of radiotherapy in the treatment of pT3N0 rectal cancer is debated and …

Background Rectal cancer is mainly cured by radical resection with neoadjuvant
chemoradiation or adjuvant chemotherapy. Pathological T1 lesions can be managed by …

Background The goal of this multicenter study was to clarify the determinants of local
excision for patients with T1–T2 lower rectal cancer. Methods Data from 567 consecutive …

Background The routine application of neoadjuvant chemoradiotherapy for T3N0 rectal
cancer remains controversial. The aim of this study was to use clinical, Magnetic resonance …

Background In locally advanced rectal cancer (LARC), beyond total mesorectal excision
(bTME) is often necessary to obtain complete resection (R0). The aim of this study was to …

Hypothesis Despite the noninclusion of locally draining lymph nodes, limited resection of
low-risk pT1 rectal cancer can achieve an adequate oncological outcome with lower …