Iron is required for the survival of most organisms, including bacteria, plants, and humans. Its
homeostasis in mammals must be fine-tuned to avoid iron deficiency with a reduced oxygen …

Iron is a constituent of many metalloproteins involved in vital metabolic functions. While
adequate iron supply is critical for health, accumulation of excess iron promotes oxidative …

In mammals, hundreds of proteins use iron in a multitude of cellular functions, including vital
processes such as mitochondrial respiration, gene regulation and DNA synthesis or repair …

Iron is essential for several vital biological processes. Its deficiency or overload drives to the
development of several pathologies. To maintain iron homeostasis, the organism controls …

The regulation and maintenance of systemic iron homeostasis is critical to human health.
Iron overload and deficiency diseases belong to the most common nutrition-related …

To maintain an adequate iron supply for hemoglobin synthesis and essential metabolic
functions while counteracting iron toxicity, humans and other vertebrates have evolved …

Iron is a vital trace element for humans, as it plays a crucial role in oxygen transport,
oxidative metabolism, cellular proliferation, and many catalytic reactions. To be beneficial …

Despite its essential role in many biological processes, iron is toxic when in excess due to its
propensity to generate reactive oxygen species. To prevent diseases associated with iron …

Sažetak Iron metabolism has been intensively examined over the last decade and there are
many new players in this field which are worth to be introduced. Since its discovery many …

Iron is an essential nutrient that is potentially toxic due to its redox reactivity. Insufficient iron
supply to erythroid cells, the major iron consumers in the body, leads to various forms of …