Functional multipotency of stem cells and recovery neurobiology of injured spinal cords

YD Teng - Cell transplantation, 2019 - journals.sagepub.com
This invited concise review was written for the special issue of Cell Transplantation to
celebrate the 25th anniversary of the American Society for Neural Therapy and Repair …

The leading edge: Emerging neuroprotective and neuroregenerative cell-based therapies for spinal cord injury

CS Ahuja, A Mothe, M Khazaei… - Stem cells …, 2020 - academic.oup.com
Spinal cord injuries (SCIs) are associated with tremendous physical, social, and financial
costs for millions of individuals and families worldwide. Rapid delivery of specialized …

Stem cells for spinal cord injury: Strategies to inform differentiation and transplantation

NR Iyer, TS Wilems… - Biotechnology and …, 2017 - Wiley Online Library
The complex pathology of spinal cord injury (SCI), involving a cascade of secondary events
and the formation of inhibitory barriers, hampers regeneration across the lesion site and …

Concise review: bridging the gap: novel neuroregenerative and neuroprotective strategies in spinal cord injury

CS Ahuja, M Fehlings - Stem cells translational medicine, 2016 - academic.oup.com
Spinal cord injuries (SCIs) result in devastating lifelong disability for patients and their
families. The initial mechanical trauma is followed by a damaging secondary injury cascade …

[HTML][HTML] Regeneration of spinal cord connectivity through stem cell transplantation and biomaterial scaffolds

H Katoh, K Yokota, MG Fehlings - Frontiers in cellular neuroscience, 2019 - frontiersin.org
Significant progress has been made in the treatment of spinal cord injury (SCI). Advances in
post-trauma management and intensive rehabilitation have significantly improved the …

Transplanting cells for spinal cord repair: who, what, when, where and why?

LV Zholudeva, MA Lane - Cell Transplantation, 2019 - journals.sagepub.com
Cellular transplantation for repair of the injured spinal cord has a rich history with strategies
focused on neuroprotection, immunomodulation, and neural reconstruction. The goal of the …

[HTML][HTML] Regulating endogenous neural stem cell activation to promote spinal cord injury repair

EAB Gilbert, N Lakshman, KSK Lau, CM Morshead - Cells, 2022 - mdpi.com
Spinal cord injury (SCI) affects millions of individuals worldwide. Currently, there is no cure,
and treatment options to promote neural recovery are limited. An innovative approach to …

[HTML][HTML] Choosing the right cell for spinal cord repair

LV Zholudeva, MA Lane - Journal of neuroscience research, 2019 - ncbi.nlm.nih.gov
There is a rich history of neural progenitor transplantation for repair of the injured central
nervous system (Anderson, Howland, & Reier, 1995; Bonner & Steward, 2015; Jakeman & …

[HTML][HTML] Cellular treatments for spinal cord injury: the time is right for clinical trials

MG Fehlings, R Vawda - Neurotherapeutics, 2011 - Elsevier
More than 1 million people in the United States live with a spinal cord injury (SCI). Despite
medical advances, many patients with SCIs still experience substantial neurological …

[HTML][HTML] Combinatorial strategies for cell transplantation in traumatic spinal cord injury

V Jagrit, J Koffler, JN Dulin - Frontiers in Neuroscience, 2024 - frontiersin.org
Spinal cord injury (SCI) substantially reduces the quality of life of affected individuals.
Recovery of function is therefore a primary concern of the patient population and a primary …