Sample preparation optimization in fecal metabolic profiling

O Deda, AC Chatziioannou, S Fasoula… - … of Chromatography B, 2017 - Elsevier
Metabolomic analysis of feces can provide useful insight on the metabolic status, the
health/disease state of the human/animal and the symbiosis with the gut microbiome. As a …

Metabolomic analysis—Addressing NMR and LC-MS related problems in human feces sample preparation

S Moosmang, M Pitscheider, S Sturm, C Seger… - Clinica Chimica …, 2019 - Elsevier
Metabolomics is a well-established field in fundamental clinical research with applications in
different human body fluids. However, metabolomic investigations in feces are currently an …

Rat fecal metabolomics-based analysis

O Deda, HG Gika, GA Theodoridis - Metabolic Profiling: Methods and …, 2018 - Springer
Fecal metabolomics-based analysis indisputably constitutes a very useful tool for elucidating
the biochemistry of digestion and absorption of the gastrointestinal system. Fecal samples …

An overview of fecal sample preparation for global metabolic profiling

O Deda, HG Gika, ID Wilson, GA Theodoridis - Journal of pharmaceutical …, 2015 - Elsevier
The global metabolic profiling of feces represents a challenge for both analytical chemistry
and biochemistry standpoints. As a specimen, feces is complex, not homogenous and rich in …

Metabolomics of fecal samples: a practical consideration

S Matysik, CI Le Roy, G Liebisch, SP Claus - Trends in Food Science & …, 2016 - Elsevier
Background Metabolic profiling is becoming increasingly popular to identify subtle metabolic
variations induced by diet alterations and to characterize the metabolic impact of variations …

Strategy for nuclear-magnetic-resonance-based metabolomics of human feces

S Lamichhane, CC Yde, MS Schmedes… - Analytical …, 2015 - ACS Publications
Metabolomic analyses of fecal material are gaining increasing attention because the gut
microbial ecology and activity have an impact on the human phenotype and regulate host …

Assessment of Biphasic Extraction Methods of Mouse Fecal Metabolites for Liquid Chromatography–Mass Spectrometry-Based Metabolomic Studies

S Yu, J Fan, L Zhang, X Qin, Z Li - Journal of Proteome Research, 2021 - ACS Publications
With the increasing knowledge about the important roles of gut microbiota on the biological
system, a systematic strategy to profile the fecal metabolome is urgently needed. Thus, an …

MR metabolomics of fecal extracts: applications in the study of bowel diseases

T Bezabeh, RL Somorjai… - Magnetic Resonance in …, 2009 - Wiley Online Library
NMR‐based metabolomics is becoming a useful tool in the study of body fluids and has a
strong potential to contribute to disease diagnosis. While applications on urine and serum …

Mass spectrometry-based fecal metabolome analysis

J Xu, QF Zhang, J Zheng, BF Yuan, YQ Feng - TrAC Trends in Analytical …, 2019 - Elsevier
The past decade has witnessed remarkable progress in our understanding of the important
roles that gut microbial metabolites play in modulating the human health. The dynamic …

A review on human fecal metabolomics: Methods, applications and the human fecal metabolome database

N Karu, L Deng, M Slae, AC Guo, T Sajed, H Huynh… - Analytica chimica …, 2018 - Elsevier
Metabolomic analysis of human biospecimens had progressed quickly over the past
decade. Technological and methodological advances have led to the comprehensive …