As understanding of host immune responses towards implanted biomaterials has grown,
macrophages have been identified as critical predictors of inflammatory consequences …

A key goal for implanted medical devices is that they do not elicit a detrimental immune
response. Macrophages play critical roles in the modulation of the host immune response …

Implants, transplants, and implantable biomedical devices are mainstream solutions for a
wide variety of human pathologies. One of the persistent problems around nondegradable …

Abstract The Three-dimensional OrbiTrap Secondary Ion Mass Spectrometry (3D OrbiSIMS)
is a secondary ion mass spectrometry instrument, a combination of a Time of Flight (ToF) …

Tissue repair, regeneration, and fibrosis are processes regulated by inflammatory
monocytes and monocyte-derived macrophages (MDMs) that circulate in peripheral blood or …

The host macrophage response is now well recognized as a predictor of the success or
failure of biomaterial implants following placement. More specifically, shifts from an “M1” pro …

Biomaterials have become indispensable in medical practice. Implants and medical devices
such as vascular grafts, heart valves, dental implants, or pacemakers and biosensors …

Inflammatory responses to biomaterials heavily influence the environment surrounding
implanted devices, often producing foreign‐body reactions. The macrophage is a key …

Macrophages play a central role in guiding proper organ and tissue development,
physiological healing, and in maintaining tissue homeostasis. Further, they are one of the …

This textbook is intended to be a resource for biomaterial scientists and biomedical
engineers, in both industry and academia, interested in the development of smart strategies …