Diabetes-induced male infertility: potential mechanisms and treatment options

R Huang, J Chen, B Guo, C Jiang, W Sun - Molecular Medicine, 2024 - Springer
Male infertility is a physiological phenomenon in which a man is unable to impregnate a
fertile woman during a 12-month period of continuous, unprotected sexual intercourse. A …

Diabetes and Male Infertility

DA Asafu-Adjei, PR Gittens - Male Infertility: Contemporary Clinical …, 2020 - Springer
Diabetes mellitus is one of the most common medical conditions in the world. One of its
major effects includes its impact on the male reproductive system. Up to 90% of diabetic men …

Diabetes mellitus causes male reproductive dysfunction: A review of the evidence and mechanisms

Z He, G Yin, QQ Li, Q Zeng, J Duan - in vivo, 2021 - iv.iiarjournals.org
The metabolic disorders caused by diabetes can lead to various complications, including
dysfunction of the male reproductive system. In patients with diabetes, long-term …

The hidden impact of diabetes on male sexual dysfunction and fertility

DRJ Glenn, N McClure, SEM Lewis - Human Fertility, 2003 - Taylor & Francis
Diabetes affects an increasingly large number of young men of reproductive age. Erectile
and ejaculatory difficulties arise due to vascular and neuropathic problems. The treatment of …

Investigating the therapeutic options for diabetes‐associated male infertility as illustrated in animal experimental models

G Tsampoukas, T Tharakan, Y Narayan, F Khan… - Andrologia, 2022 - Wiley Online Library
Diabetes is a rising global health concern and an increasingly common cause of male
infertility. Although the definitive pathophysiological mechanisms underpinning the …

Diabetes mellitus and the impairment of male reproductive function: Possible signaling pathways

S Barkabi-Zanjani, V Ghorbanzadeh, M Aslani… - Diabetes & Metabolic …, 2020 - Elsevier
Background and aims Today, it has been shown that diabetes mellitus (DM) can affect male
fertility. Glucose metabolism is a vital process in spermatogenesis that is impacted by …

Abnormalities in sex hormones and sexual dysfunction in males with diabetes mellitus: A mechanistic insight

N Andlib, M Sajad, R Kumar, SC Thakur - Acta Histochemica, 2023 - Elsevier
Diabetes is a considerate metabolic disorder that can lead to a series of complications,
involving the malfunctioning of the reproductive system of males. It has been observed that …

Diabetes mellitus and infertility: different pathophysiological effects in type 1 and type 2 on sperm function

RA Condorelli, S La Vignera, LM Mongioì… - Frontiers in …, 2018 - frontiersin.org
Although the prevalence of sub-infertility in diabetic patients in childbearing age is known,
the mechanisms by which diabetes mellitus (DM) causes male infertility are not completely …

Antidiabetic therapies and male reproductive function: where do we stand?

RS Tavares, S Escada-Rebelo, AF Silva… - …, 2018 - rep.bioscientifica.com
Diabetes mellitus has been increasing at alarming rates in recent years, thus jeopardizing
human health worldwide. Several antidiabetic drugs have been introduced in the market to …

Diabetes associated with male reproductive system damages: Onset of presentation, pathophysiological mechanisms and drug intervention

GJ Shi, ZM Li, J Zheng, J Chen, XX Han, J Wu… - Biomedicine & …, 2017 - Elsevier
Diabetes mellitus (DM) is a major health problem that affects patients' quality of life quality
throughout the world due to its many complications. Reproductive dysfunction is one of the …