The oral cavity is the habitat of several hundreds of microbial taxa that have evolved to
coexist in multispecies communities in this unique ecosystem. By contrast, the internal tissue …

Microbiota are found in highly organized and complex entities, known as biofilms, the
characteristics of which are fundamentally different from microbes in planktonic …

Endodontic microbiology deals with the study of the microbial aetiology and pathogenesis of
pulpal and periradicular inflammatory diseases. Research in endodontic microbiology …

Endodontic disease, a biofilm infection of the root canal space, is a significant cause of
dental morbidity worldwide. Endodontic treatment, or root canal treatment, as it is commonly …

Current concepts suggest that persisting infections subsequent to endodontic therapy are
caused by one or two bacterial species that are “too robust” to be eliminated by conventional …

INTRODUCTION: Clinical/microbiological studies have consistently revealed the
persistence of some bacteria after conventional root canal debridement. Although this was …

Limitations in endodontic disinfection are collectively due to the biofilm mode of bacteria in
root canal systems, anatomical complexities, dentin structure/composition, and limitations …

Next‐generation sequencing (NGS) has now been applied for a decade to characterize the
microbiota composition of infected dental root canals associated with apical periodontitis …

Pulp regeneration is considered in cases where the dental pulp has been destroyed
because of microbial irritation. Diverse oral and food-borne micro-organisms are able to …

Endodontic disease is a biofilm-mediated infection, and primary aim in the management of
endodontic disease is the elimination of bacterial biofilm from the root canal system. The …