Ciprofloxacin hydrochloride has a short elimination half-life, a narrow absorption window
and is mainly absorbed in proximal areas of GIT. The purpose of this study was to develop a …

Ciprofloxacin is mainly absorbed in the proximal areas of the gastrointestinal tract. The
purpose of our study was production of floating-bioadhesive tablets to lengthen the stay of …

Sažetak Floating matrix tablets of norfloxacin were developed to prolong gastric residence
time, leading to an increase in drug bioavailability. Tablets were prepared by the wet …

Drugs that have narrow absorption window in the gastrointestinal tract (GIT) will have poor
absorption. For these drugs, gastroretentive drug delivery systems offer the advantage in …

This study aimed to develop hydrophilic matrix based controlled release gastroretentive
drug delivery system of ofloxacin and conducting its in vitro and in vivo evaluations …

To prolong the residence time of dosage forms within gastrointestinal trace until all drug
released at desired rate was one of the real challenges for oral controlled-release drug …

The aim of this work was to design and evaluate effervescent floating gastro-retentive drug
delivery matrix tablets with sustained-release behavior using a binary mixture of …

The fluroquinolone anti-biotic ciprofloxacin is primarily dissolved and absorbed from the
upper part of the GI tract. We, therefore, aimed to develop a prolonged release …

Oral sustained release gastroretentive dosage forms offer many advantages for drugs
having absorption from upper gastrointestinal tract and improve the bioavailability of …

Sustained release (SR)-gastroretentive dosage forms (GRDF) enable prolonged and
continuous input of the drug to the upper parts of the gastrointestinal (GI) tract and improve …