[HTML][HTML] Role of advanced glycation end products in cellular signaling
C Ott, K Jacobs, E Haucke, AN Santos, T Grune… - Redox biology, 2014 - Elsevier
Improvements in health care and lifestyle have led to an elevated lifespan and increased
focus on age-associated diseases, such as neurodegeneration, cardiovascular disease …
focus on age-associated diseases, such as neurodegeneration, cardiovascular disease …
Molecular effects of advanced glycation end products on cell signalling pathways, ageing and pathophysiology
Advanced glycation end-products (AGEs) are a heterogeneous group of compounds formed
by the Maillard chemical process of non-enzymatic glycation of free amino groups of …
by the Maillard chemical process of non-enzymatic glycation of free amino groups of …
Does accumulation of advanced glycation end products contribute to the aging phenotype?
RD Semba, EJ Nicklett, L Ferrucci - Journals of Gerontology …, 2010 - academic.oup.com
Background. Aging is a complex multifactorial process characterized by accumulation of
deleterious changes in cells and tissues, progressive deterioration of structural integrity and …
deleterious changes in cells and tissues, progressive deterioration of structural integrity and …
Kidney, heart and brain: three organs targeted by ageing and glycation
M Frimat, M Daroux, R Litke, R Nevière… - Clinical …, 2017 - portlandpress.com
Advanced glycation end-product (AGE) is the generic term for a heterogeneous group of
derivatives arising from a non-enzymatic reaction between reducing sugars and proteins. In …
derivatives arising from a non-enzymatic reaction between reducing sugars and proteins. In …
Clinical/translational aspects of advanced glycation end-products
C Zeng, Y Li, J Ma, L Niu, FR Tay - Trends in Endocrinology & Metabolism, 2019 - cell.com
Advanced glycation end-products (AGEs) have been implicated in chronic hyperglycemia
and age-related diseases. Endogenous AGEs produced by humans generate oxidative …
and age-related diseases. Endogenous AGEs produced by humans generate oxidative …
Food-derived advanced glycation end products (AGEs): a novel therapeutic target for various disorders
S Yamagishi, S Ueda, S Okuda - Current pharmaceutical …, 2007 - ingentaconnect.com
Non-enzymatic modification of proteins by reducing sugars, a process that is also known as
Maillard reaction, leads to the formation of advanced glycation end products (AGEs) in vivo …
Maillard reaction, leads to the formation of advanced glycation end products (AGEs) in vivo …
[HTML][HTML] Advanced glycation end products: a molecular target for vascular complications in diabetes
S Yamagishi, N Nakamura, M Suematsu, K Kaseda… - Molecular …, 2015 - Springer
A nonenzymatic reaction between reducing sugars and amino groups of proteins, lipids and
nucleic acids contributes to the aging of macromolecules and subsequently alters their …
nucleic acids contributes to the aging of macromolecules and subsequently alters their …
Advanced glycation end products and RAGE: a common thread in aging, diabetes, neurodegeneration, and inflammation
R Ramasamy, SJ Vannucci, SSD Yan, K Herold… - …, 2005 - academic.oup.com
The products of nonenzymatic glycation and oxidation of proteins and lipids, the advanced
glycation end products (AGEs), accumulate in a wide variety of environments. AGEs may be …
glycation end products (AGEs), accumulate in a wide variety of environments. AGEs may be …
Advanced glycation end products and their receptor in age-related, non-communicable chronic inflammatory diseases; Overview of clinical evidence and potential …
NL Reynaert, P Gopal, EPA Rutten… - The international journal …, 2016 - Elsevier
Age-related, non-communicable chronic inflammatory diseases represent the major 21st
century health problem. Especially in Western countries, the prevalence of non …
century health problem. Especially in Western countries, the prevalence of non …
[HTML][HTML] Advanced glycation end-products produced systemically and by macrophages: A common contributor to inflammation and degenerative diseases
Advanced glycation end products (AGEs) and their receptor have been implicated in the
progressions of many intractable diseases, such as diabetes and atherosclerosis, and are …
progressions of many intractable diseases, such as diabetes and atherosclerosis, and are …