Tetrameric organization of vertebrate centromeric nucleosomes
EK Dimitriadis, C Weber, RK Gill… - Proceedings of the …, 2010 - National Acad Sciences
Mitosis ensures equal genome segregation in the eukaryotic lineage. This process is
facilitated by microtubule attachment to each chromosome via its centromere. In …
facilitated by microtubule attachment to each chromosome via its centromere. In …
The octamer is the major form of CENP-A nucleosomes at human centromeres
D Hasson, T Panchenko, KJ Salimian… - Nature structural & …, 2013 - nature.com
The centromere is the chromosomal locus that ensures fidelity in genome transmission at
cell division. Centromere protein A (CENP-A) is a histone H3 variant that specifies …
cell division. Centromere protein A (CENP-A) is a histone H3 variant that specifies …
An epigenetic mark generated by the incorporation of CENP-A into centromeric nucleosomes
Mammalian centromeres are defined epigenetically. Although the physical nature of the
epigenetic mark is unknown, nucleosomes in which CENP-A replaces histone H3 are at the …
epigenetic mark is unknown, nucleosomes in which CENP-A replaces histone H3 are at the …
[HTML][HTML] Epigenetic centromere propagation and the nature of CENP-a nucleosomes
BE Black, DW Cleveland - Cell, 2011 - cell.com
Centromeres direct chromosome inheritance, but in multicellular organisms their positions
on chromosomes are primarily specified epigenetically rather than by a DNA sequence. The …
on chromosomes are primarily specified epigenetically rather than by a DNA sequence. The …
CENP-A nucleosome—a chromatin-embedded pedestal for the centromere: lessons learned from structural biology
A Ali-Ahmad, N Sekulić - Essays in Biochemistry, 2020 - portlandpress.com
The centromere is a chromosome locus that directs equal segregation of chromosomes
during cell division. A nucleosome containing the histone H3 variant CENP-A epigenetically …
during cell division. A nucleosome containing the histone H3 variant CENP-A epigenetically …
Dual recognition of CENP-A nucleosomes is required for centromere assembly
CW Carroll, KJ Milks, AF Straight - Journal of Cell Biology, 2010 - rupress.org
Centromeres contain specialized nucleosomes in which histone H3 is replaced by the
histone variant centromere protein A (CENP-A). CENP-A nucleosomes are thought to act as …
histone variant centromere protein A (CENP-A). CENP-A nucleosomes are thought to act as …
Crystal structure of the human centromeric nucleosome containing CENP-A
H Tachiwana, W Kagawa, T Shiga, A Osakabe, Y Miya… - Nature, 2011 - nature.com
In eukaryotes, accurate chromosome segregation during mitosis and meiosis is coordinated
by kinetochores, which are unique chromosomal sites for microtubule attachment …
by kinetochores, which are unique chromosomal sites for microtubule attachment …
Constitutive centromere-associated network contacts confer differential stability on CENP-A nucleosomes in vitro and in the cell
Eukaryotic centromeres are defined by the presence of nucleosomes containing the histone
H3 variant, centromere protein A (CENP-A). Once incorporated at centromeres, CENP-A …
H3 variant, centromere protein A (CENP-A). Once incorporated at centromeres, CENP-A …
The molecular basis for centromere identity and function
KL McKinley, IM Cheeseman - Nature reviews Molecular cell biology, 2016 - nature.com
The centromere is the region of the chromosome that directs its segregation in mitosis and
meiosis. Although the functional importance of the centromere has been appreciated for …
meiosis. Although the functional importance of the centromere has been appreciated for …
[HTML][HTML] Tetrameric Structure of Centromeric Nucleosomes in Interphase Drosophila Cells
Centromeres, the specialized chromatin structures that are responsible for equal
segregation of chromosomes at mitosis, are epigenetically maintained by a centromere …
segregation of chromosomes at mitosis, are epigenetically maintained by a centromere …