Effect of remote ischemic conditioning on the immune-inflammatory profile in patients with traumatic hemorrhagic shock in a randomized controlled trial

CH Leung, SB Rizoli, S Trypcic, SG Rhind… - Scientific Reports, 2023 - nature.com
Resuscitation induced ischemia/reperfusion predisposes trauma patients to systemic
inflammation and organ dysfunction. We investigated the effect of remote ischemic …

Remote ischemic conditioning prevents lung and liver injury after hemorrhagic shock/resuscitation: potential role of a humoral plasma factor

CH Leung, CA Caldarone, F Wang… - Annals of …, 2015 - journals.lww.com
Objective: To evaluate the efficacy of remote ischemic conditioning (RIC) on organ
protection after hemorrhagic shock/resuscitation (S/R) in a murine model. Background …

Survival benefits of remote ischemic conditioning in sepsis

B Joseph, M Khalil, A Hashmi, L Hecker… - Journal of Surgical …, 2017 - Elsevier
Background Sepsis remains the leading cause of death in the surgical intensive care unit.
Prior studies have demonstrated a survival benefit of remote ischemic conditioning (RIC) in …

Effect of remote ischemic post-conditioning on systemic inflammatory response and survival rate in lipopolysaccharide-induced systemic inflammation model

YH Kim, DW Yoon, JH Kim, JH Lee, CH Lim - Journal of inflammation, 2014 - Springer
Background Remote ischemic preconditioning (RIPC) and postconditioning (RpostC) have
protective effects on ischemia and reperfusion injury. The effects have been reported to …

Remote ischemic post-conditioning promotes hematoma resolution via AMPK-dependent immune regulation

K Vaibhav, M Braun, MB Khan, S Fatima… - Journal of Experimental …, 2018 - rupress.org
Spontaneous intracerebral hemorrhage (ICH) produces the highest acute mortality and
worst outcomes of all stroke subtypes. Hematoma volume is an independent determinant of …

Secondary brain injury in trauma patients: the effects of remote ischemic conditioning

B Joseph, V Pandit, B Zangbar… - Journal of Trauma …, 2015 - journals.lww.com
BACKGROUND Management of traumatic brain injury (TBI) is focused on preventing
secondary brain injury. Remote ischemic conditioning (RIC) is an established treatment …

Hypertonic resuscitation modulates the inflammatory response in patients with traumatic hemorrhagic shock

EM Bulger, J Cuschieri, K Warner, RV Maier - Annals of surgery, 2007 - journals.lww.com
Objective: To determine the effect of resuscitation with hypertonic saline/dextran (HSD) on
the innate immune response after injury. Summary of Background Data: Hypovolemic shock …

Remote ischemic preconditioning prevents lipopolysaccharide-induced liver injury through inhibition of NF-κB activation in mice

HJ Shin, NH Won, HW Lee - Journal of anesthesia, 2014 - Springer
Purpose Remote ischemic preconditioning (RIPC) is a potent preconditioning stimulus that
may confer subsequent protection to organs subjected to potentially lethal injury. The aim of …

Effectiveness of remote ischaemic conditioning is not affected by hyper-inflammation in a rat model of stroke

J Končeková, K Kotorová, M Némethová, M Bona… - Scientific Reports, 2024 - nature.com
The inflammation and coagulopathy during coronavirus disease (COVID-19) impairs the
efficiency of the current stroke treatments. Remote ischaemic conditioning (RIC) has shown …

Remote ischemic conditioning in septic shock (RECO-Sepsis): study protocol for a randomized controlled trial

M Cour, M Buisson, K Klouche, R Bouzgarrou… - Trials, 2019 - Springer
Background Septic shock is a major public health problem that is associated with up to 50%
mortality. Unfavorable outcomes are mainly attributed to multiple organ failure (MOF) …