Molecular diagnostics in the evaluation of thyroid nodules: current use and prospective opportunities

J Patel, J Klopper, EE Cottrill - Frontiers in endocrinology, 2023 - frontiersin.org
Thyroid cancer is the most common endocrine malignancy with an estimated 43,800 new
cases to be diagnosed in 2022 and representing the 7th most common cancer in women …

Molecular testing in thyroid cancer diagnosis and management

JA Sipos, MD Ringel - Best Practice & Research Clinical Endocrinology & …, 2023 - Elsevier
Molecular diagnostic testing has had a profound impact on the diagnosis and management
of thyroid nodules and thyroid cancer. Based on the tremendous expansion of knowledge of …

Clinical value of molecular markers as diagnostic and prognostic tools to guide treatment of thyroid cancer

P Valderrabano, M Eszlinger… - Clinical …, 2023 - Wiley Online Library
Objective Advances in our understanding of the molecular biology of thyroid tumours is
being rapidly translated into their clinical management. This review summarizes the current …

Molecular testing for thyroid nodules: review and current state

MY Roth, RL Witt, DL Steward - Cancer, 2018 - Wiley Online Library
Thyroid nodules affect nearly two‐thirds of the world population. Fine‐needle biopsy with
cytologic evaluation remains the diagnostic test of choice to distinguish benign from …

Molecular testing for thyroid nodules including its interpretation and use in clinical practice

SG Patel, SE Carty, AJ Lee - Annals of surgical oncology, 2021 - Springer
Despite advances in imaging and biopsy techniques, the management of thyroid nodules
often remains a diagnostic and clinical challenge. In particular, patients with cytologically …

Molecular diagnostic evaluation of thyroid nodules

SE Mayson, BR Haugen - Endocrinology and Metabolism …, 2019 - endo.theclinics.com
The historical management of thyroid nodules with indeterminate cytology has often been
with diagnostic lobectomy or thyroidectomy. There is a substantial downside to this …

Thyroid nodule molecular testing: is it ready for prime time?

TM Khan, MA Zeiger - Frontiers in Endocrinology, 2020 - frontiersin.org
Cytologically indeterminate thyroid nodules remain a diagnostic and clinical challenge, and
molecular testing has been advocated and advanced as a diagnostic modality to help guide …

Molecular testing for thyroid nodules: Where are we now?

C Ferraz - Reviews in Endocrine and Metabolic Disorders, 2024 - Springer
Approximately 25% of the fine needle aspiration samples (FNAB) of thyroid nodules are
classified as “indeterminate samples”, that means, Bethesda III and IV categories. Until the …

Diagnostic use of molecular markers in the evaluation of thyroid nodules

MI Kim, EK Alexander - Endocrine Practice, 2012 - Elsevier
Objective To describe the molecular markers thus far evaluated for use in the care of
patients with clinically relevant thyroid nodules. Methods We review the currently available …

New strategies in diagnosing cancer in thyroid nodules: impact of molecular markers

YE Nikiforov, L Yip, MN Nikiforova - Clinical cancer research, 2013 - AACR
Thyroid cancer is the most common type of endocrine malignancy, with approximately
55,000 new cases diagnosed in the United States in 2012. However, thyroid nodules are …